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Completed

NCT Number: NCT05985616

High Intensity Resistance Training and Possible Sarcopenia

Studies conducted so far added the dietary supplements along with resistance training as an intervention, we could not determine whether the observed effects of the intervention were due to the training program and/or dietary supplements.

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Key information

Conditions

Sarcopenia Atrophy Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Abbas Institute of Medical Sciences

Muzaffarabad, Azad Kashmir, Pakistan

About this study

This study will investigate the effects of high intensity resistance training solely in the possible sarcopenia cases which has not done before, to author's knowledge. Furthermore this study will help clinicians to individualize and optimize the therapy for specific patient subgroups, improve the potential of this therapy to improve human function and well being, facilitate timely interventions in community healthcare and prevention settings, which will contribute to higher awareness of sarcopenia prevention and interventions in diverse health care settings.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Both male and female
  • Age more than 60 years
  • Possible sarcopenia cases as defined by Asian Working Group for Sarcopenia (Handgrip strength: Male less than 26kg and Female less than 18kg, 5 time chair stand test more than/equals to 12 seconds)

Exclusion criteria

  • Orthopedic surgery in last one year
  • Neurological disorders like stroke etc
  • History of recent fractures
  • Metabolic disorders like DM etc
  • Actively involved in exercise programs
  • Cognitive impairment that could confound the assessment
  • Wheelchair or bed bound individuals

Treatment and study plan

High Intensity Resistance Training

Other

High intensity resistance training will be performed 3 times a day for sixteen weeks

Primary outcomes

  1. Hand Dynamometer

    Time frame: 16 weeks

    it used to measure the hand grip strength. the test-retest reliability is 0.91 and 0.95 with excellent reliability. The assessment will be made at baseline, week 8 and 16

  2. Short performance physical battery

    Time frame: 16 Week

    an objective assessment tool for evaluating lower extremity functioning in older persons. the test-retest reliability is 0.87. It was used to measure at baseline, week 8 and 16

Secondary outcomes

  1. FRAIL

    Time frame: 16 week

    The questionnaire aims at fatigue, resistance, ambulation, illness and loss of weight. It is a self reported questionnaire. The sensitivity of FRAIL is 85.8% and a specificity of 80.6%.

    The test will be measured at baseline, week 8 and 16

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects of High Intensity Resistance Training on Physical Function in Possible Sarcopenia Cases

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Aug 14, 2023
Registry last updated
Mar 5, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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