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Completed

NCT Number: NCT02318459

High Intensity Interval Training in Geriatrics

This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.

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Key information

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hôpital des Trois-Chêne (HUG)

Geneva, Thônex, 1226, Switzerland

About this study

High Intensity Interval Training (HIIT) has shown a superior effectiveness and efficiency when compared to Moderate Intensity Continuous Training (MICT) in several types of patients and in healthy subjects. There are no data on HIIT in a general geriatric population. This study is a pilot study evaluating the feasibility of using HIIT in geriatric hospitalized patients compared to the standard current rehabilitation practice without HIIT. It is our desire to perform a larger randomized comparative trial between HIIT and MICT if the pilot study proves its feasibility.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 65 years and older hospitalized for rehabilitation after an acute medical condition
  • Expected duration of the rehabilitation ≥ 2 weeks
  • Ability to follow instructions to perform a Timed up and Go Test
  • Ability to perform exercises
  • Willing to participate in 4 sessions of HIIT per week for 2 weeks

Exclusion criteria

  • Any acute condition with tachycardia, hypotension or fever.
  • Abnormal cycle ergometer stress test with
  • significant ECG modification
  • decrease of more than 20 mmHg of the blood pressure with exercise
  • angina
  • ST depression at a workload <6 METs
  • Inability to reach an intensity of 15/20 in the Borg's scale of perceived exertion
  • Any unresolved acute medical or surgical condition of the following kind:
  • acute heart failure
  • acute coronary syndrome < 1 month
  • strole < 1 month
  • active pericarditis / myocarditis / endocarditis
  • thromboembolic disease with < 2 weeks of anticoagulation
  • acute infection requiring intravenous treatment
  • ongoing intravenous perfusion
  • surgery < 2 months
  • recent bone fracture
  • Previous episode of primary cardiac arrest (ie, cardiac arrest that did not occur in the presence of an acute myocardial infarction or during a cardiac procedure).
  • Severe heart failure (NYHA III and IV)
  • Severe stenotic or regurgitant valvular disease
  • Uncontrolled hypertension at rest (SBP≥160mmHg, DBP≥100mmHg)
  • Uncontrolled dysrhythmia
  • Non-sustained ventricular tachycardia with exercise
  • Implanted defibrillator
  • Obstructive cardiomyopathy
  • Resting HR > 100/min
  • Severe peripheral artery disease
  • Severe COPD (VEMS < 50%)
  • Exercise-induced asthma
  • Oxygen dependency
  • Muscular-skeletal anomaly that may limit exercise participation
  • Delirium
  • Inability to follow instructions
  • Inability to consent

Treatment and study plan

high intensity interval training-HIIT

Other

HIIT 4 times a week, 30 minutes duration

Traditionnal group rehabilitation

Other

Traditionnal group rehabilitation, 3 times a week, 1 hour duration

Primary outcomes

  1. Proportion of patients who complete the rehabilitation program

    Time frame: 2 weeks

Secondary outcomes

  1. Distance walked in the 6MWT

    Time frame: 2 weeks

  2. Muscle strength assessed for the upper and lower extremities

    Time frame: 2 weeks

    upper extremity : handgrip strength using the Baseline Pneumatic Bulb Hand Dynamometer Pinch Gauge; Lower exremity : knee flexion & extension and ankle flexion & extension using Microfet2™portable Dynamometer.

  3. Step variability changes as a measure of quality of ambulation

    Time frame: 2 weeks

    Variability measured with GaitRite step analysis system

Sponsors and collaborators

Lead sponsor

University Hospital, Geneva

Other

Registry information

Official study title

High Intensity Interval Training for thE Rehabilitation of Geriatric Patients - a Feasibility Pilot studY.

Acronym: HIITERGY

Important dates

Study start
2014
Primary completion
2015
Study completion
2016
First posted
Dec 17, 2014
Registry last updated
Nov 3, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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