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Completed

NCT Number: NCT05821504

High-Intensity Interval Training and Performance

The goal of this clinical trial was to compare to different types of high-intensity interval training in young, healthy females. The main questions were: Will changes in body composition differ between the two interventions? Will changes in endurance and muscle performance differ between the two interventions? Participants were randomized to 8 weeks of high-intensity interval training involving body weight, plyometric exercises or cycling only. Researchers compared changes in endurance performance, body composition, and muscle performance to determine if there were differences between groups.

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Key information

Conditions

Age range

18 year–35 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Kennesaw State University

Kennesaw, Georgia, 30144, United States

About this study

The purpose of this study was to compare the effects of plyometric- and cycle-oriented high-intensity interval training on body composition, aerobic capacity, and skeletal muscle size, quality, and function in recreationally trained females. Young (21.7 ± 3.1 yrs), recreationally active females were randomly assigned to 8 weeks of twice weekly plyometric (n = 15) or cycling (n = 15) high-intensity interval training. The plyometric-oriented Les Mills BODYATTACK program was used for the plyometric group whereas Les Mills SPRINT, which exclusively involves stationary cycling, represented the cycling group. Both protocols involved alternating high-intensity and recovery intervals, and participants were consistently instructed to give maximal effort during the 'work' periods.

The 30 min plyometric routines included four blocks of high-intensity exercise intervals. The 'work' portions consisted of the following exercises: high-knee runs, plyometric lunges, jumping jacks, squat jumps, burpees, and speed-agility patterns. The recovery periods consisted of complete rest (transitioning between exercises), a light jog, or a low impact stepping motion. On average, participants were instructed to give maximal effort for 1-2 min, with recovery intervals of 15-45 sec. Four separate routines were used throughout the duration of the study, keeping one routine per week; participants completed each routine a total of 4 times within a session.

The 30 min cycling routines were performed on upright stationary bikes (Schwinn, AC Performance, Chicago, IL). Protocols involved 'work' ranging from 20-80 sec with recovery intervals between 10-60 sec. Recovery intervals consisted of complete rest on bike or particularly slow cycling. Resistance and cycling speed were relatively variable across sessions, with some intervals of higher resistance and lower speed and others involving lower resistance and higher speed (e.g., >120 RPMs). The same four workouts were used throughout the duration of the study alternating each week.

Body composition (4-compartment model), VO2peak, countermovement jump performance, muscle size and echo intensity (muscle quality) as well as strength and power of the knee extensors and plantar flexors were measured before and after training. Body composition testing was completing using dual-energy x-ray absorpiometry, air displacement plethysmogrphay, and bioeletrical impedance. VO2peak was measured using a standardized maximal exercise test on a treadmill. Countermovement jump height and power was recorded with participants performing jumps on a force plate. Muscle size and quality were determined using non-invasive ultrasonography. Finally, serum growth hormone responses to the VO2peak test were measured before and after the protocols.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between 18-35 years of age
  • Female
  • Currently participating in 2-4 days of structured exercise for 30-75 minutes for the last 6 months

Exclusion criteria

  • Currently participating in these exercise formats (2x/week within last 3 months)
  • Engaging in high intensity interval training for more than 30 min/week
  • Have diagnosed disorders/diseases in the following: cardiovascular, pulmonary, immunological, or metabolic
  • Current musculoskeletal injuries
  • Pregnant or think you may be pregnant
  • Currently taking any non-steroidal anti-inflammatory drug(s) or steroidal drug(s)
  • Currently a smoker or has consistently smoked within the last year
  • Has a positive written or verbal pre-study drug screen including alcohol (more than 7 drinks/week), THC/cannabinoids, amphetamines, benzodiazepines, cocaine, opioids, phencyclidine, barbiturates, cotinine.
  • Currently taking any medication that will significantly affect your heart rate response to exercise
  • If you miss four or more classes, you will be excluded from the study

Treatment and study plan

High-intensity interval training

Behavioral

The training intervention is a popular exercise format that consist of alternating brief bouts of high-intensity efforts with bouts of light effort or complete rest.

Primary outcomes

  1. Muscle composition at baseline

    Time frame: Pre-intervention

    echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle

  2. Muscle composition after 8-week intervention

    Time frame: At week 9

    echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle

Secondary outcomes

  1. Fat mass at baseline

    Time frame: Pre-intervention

    Amount of fat tissue a person possesses

  2. Fat mass after 8-week intervention

    Time frame: At week 9

    Amount of fat tissue a person possesses

  3. Group average growth hormone response (concentration at microLiters/Liters) at baseline

    Time frame: Pre-intervention

    The acute, exercise-induced response for growth hormone

  4. Group average growth hormone response (concentration at microLiters/Liters) after 8-week intervention

    Time frame: At week 9

    The acute, exercise-induced response for growth hormone

  5. Countermovement jump height at baseline

    Time frame: Pre-intervention

    Height of jump

  6. Countermovement jump height after 8-week intervention

    Time frame: At week 9

    Height of jump

  7. Time to peak torque at baseline

    Time frame: Pre-intervention

    How quickly muscle torque is generated

  8. Time to peak torque after 8-week intervention

    Time frame: At week 9

    How quickly muscle torque is generated

  9. Maximal oxygen consumption at baseline

    Time frame: Pre-intervention

    Standard measure of maximal oxygen consumption or peak aerobic capacity during exercise

  10. Maximal oxygen consumption after 8-week intervention

    Time frame: At week 9

    Standard measure of maximal oxygen consumption or peak aerobic capacity during exercise

  11. Body fat percentage at baseline

    Time frame: Pre-intervention

    Relative amount of body fat a person possesses

  12. Body fat percentage after 8-week intervention

    Time frame: At week 9

    Relative amount of body fat a person possesses

  13. Fat-free mass at baseline

    Time frame: Pre-intervention

    Amount of non-fat tissue a person possesses

  14. Fat-free mass after 8-week intervention

    Time frame: At week 9

    Amount of non-fat tissue a person possesses

  15. Peak torque at baseline

    Time frame: Pre-intervention

    Strength of a muscle

  16. Peak torque after 8-week intervention

    Time frame: At week 9

    Strength of a muscle

  17. Muscle cross-sectional area at baseline

    Time frame: Pre-intervention

    The size of a muscle

  18. Muscle cross-sectional area after 8-week intervention

    Time frame: At week 9

    The size of a muscle

  19. Muscle power at baseline

    Time frame: Pre-intervention

    Product of torque and velocity as determined on a dynamometer

  20. Muscle power after 8-week intervention

    Time frame: At week 9

    Product of torque and velocity as determined on a dynamometer

Other outcomes

  1. Weekly exercising heart rate

    Time frame: during 8-week exercise intervention

    A descriptor of the exercise physiological intensity for both protocols

  2. Weekly exercising perceived effort

    Time frame: during 8-week exercise intervention

    Perceived intensity derived from the rating of perceived exertion scale

  3. Calorie consumption at baseline

    Time frame: Pre-intervention

    Amount of calories consumed at beginning and end of protocol

  4. Calorie consumption after 8-week intervention

    Time frame: At week 9

    Amount of calories consumed at beginning and end of protocol

  5. Protein consumption at baseline

    Time frame: Pre-intervention

    Amount of protein consumed at beginning and end of protocol

  6. Protein consumption after 8-week intervention

    Time frame: At week 9

    Amount of protein consumed at beginning and end of protocol

  7. Peak heart during maximal testing at baseline

    Time frame: Pre-intervention

    The highest heart rate attained during maximal exercise testing

  8. Peak heart during maximal testing after 8-week intervention

    Time frame: At week 9

    The highest heart rate attained during maximal exercise testing

Sponsors and collaborators

Lead sponsor

Kennesaw State University

Other

Registry information

Official study title

Effects of Plyometric- and Cycle-Based High-Intensity Interval Training on Body Composition, Aerobic Capacity, and Muscle Function in Young Females: a Field-based Group Fitness Assessment

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Apr 20, 2023
Registry last updated
Jun 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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