High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation

The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving. Outcomes are determined by the quantification and subtype of circulating microparticles, complete blood counts, and the quantification of venous gas emboli, measured via transthoracic echocardiography, in the cardiac cavities.

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Key information

Conditions

Decompression Sickness Barotrauma Behavior Motor Activity SCUBA Diving Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University of Split School of Medicine, Split, Dalmatia, Croatia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Experienced divers (> 250 logged dives)
Male
Physician clearance to dive

Exclusion criteria

Prior incidence of decompression sickness

Treatment and study plan

High Intensity Exercise

Other

Subjects performed a repeated Wingate protocol for the exercise condition of the study. This consisted of 4, 30 s maximal efforts on a weight-braked cycle ergometer (Monark 894E, Monark Exercise AB, Sweden) with 4 min active recovery between efforts, preceded by a 5 min warm up. The resistance was set at 7.5% bodyweight for the intervals and 2% for the warm up and active recovery periods.

Primary outcomes

Change from baseline values of number of circulating microparticles per microliter of blood

Time frame: Prior to exercise, prior to diving, 15 and 120 minutes after surfacing

Sponsors and collaborators

Lead sponsor

University of Split

Other

Collaborators

University of Maryland

Registry information

Important dates

Study start: 2013
Primary completion: 2013
Study completion: 2013
First posted: Feb 17, 2014
Registry last updated: Feb 17, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed