Clinical Nutrition Research Unit, National Nutrition and Food Technology Research Institute
Tehran, 19395-4741, Iran
Completed
NCT Number: NCT05589350
High-fat Yogurt and Plasma Lipids Profile
The goal of this clinical trial is to compare the effect of saturated fat intake from different source on cardiometabolic risk markers in healthy subjects. The main question it aims to answer are:
-Does intake of saturated fat in the form of high-fat yogurt have a different effect on cardiometabolic risk factors than intake of the same amount from butter? In this study, in two periods of 4 weeks, the effect of receiving saturated fat from high-fat yogurt compared to receiving the same amount of saturated fat from butter and low-fat yogurt on the plasma concentration of lipids, cholesterol, insulin, and some inflammatory factors will be studied in healthy subjects.
Completed
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Notify MeKey information
Conditions
Age range
20 year–65 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Healthy people who do not use lipid-lowering, blood pressure control or diabetes medications
Exclusion criteria
- Taking supplements of omega-3 fatty acids, or antioxidants
Treatment and study plan
saturated fat intake
OtherIntake of saturated fat from yogurt and animal butter daily for 4-week period
Primary outcomes
-
Plasma lipid profile
Time frame: 4 weeks
Plasma concentrations of cholesterol, high-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, and triglyceride
Secondary outcomes
-
Glycemic measures
Time frame: 4 weeks
Fasting plasma concentrations of glucose and insulin
Other outcomes
-
Inflammatory markers
Time frame: 4 weeks
Plasma concentrations of c-reactive protein and interleukin 6
Sponsors and collaborators
Lead sponsor
Shahid Beheshti University
Other
Registry information
Official study title
Comparison of the Impact of Saturated Fat From High-fat Yogurt or Low-fat Yogurt and Butter on Cardiometabolic Risk Markers: a Randomized Cross-over Trial
Important dates
- Study start
- 2022
- Primary completion
- 2023
- Study completion
- 2023
- First posted
- Oct 21, 2022
- Registry last updated
- Apr 18, 2023
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.