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Completed

NCT Number: NCT05725109

Hepatitis C Diagnosis to Treatment Management

The objective of this study is to evaluate whether sending alerts to healthcare providers and clinic staff to identify patients with untreated hepatitis C infection can increase the uptake of hepatitis C treatment. A period of time without alerts will be compared to a period of time with alerts.

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Key information

Conditions

Hepatitis C Blood-Borne Infections Communicable Diseases Digestive System Diseases Flaviviridae Infections Hepatitis Hepatitis, Viral, Human Infections Liver Diseases RNA Virus Infections Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

AIDS Healthcare Foundation

Los Angeles, California, 90028, United States

About this study

The hepatitis C virus (HCV) is one of the most common bloodborne pathogens in the United States. A large proportion of people with HCV infection progress to chronic HCV infection despite the availability of effective treatment; chronic infection can result in cirrhosis, end-stage liver disease, liver cancer, and liver-related death. HCV infection can be cured most of the time with treatment. The objective of this before and after study is to evaluate whether sending alerts to healthcare providers and clinic staff to identify patients with untreated hepatitis C infection can increase the uptake of HCV treatment. A period of time without alerts will be compared to a period of time with alerts. Healthcare providers and clinic staff will not receive alerts during the before period of the study. Healthcare providers and clinic staff will receive alerts during the after period of the study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18+ years of age
  • In care at an AIDS Healthcare Foundation Healthcare Center
  • Active, untreated HCV infection

Exclusion criteria

  • <18 years of age
  • Patients with active HCV infection who have a current prescription for HCV treatment

Treatment and study plan

Hepatitis C Treatment Alerts in CHORUS™

Other

Clinical Health Outcomes Reporting & Utilization Service (CHORUS™) is a web-based healthcare analytics and reporting solution that transforms electronic health record data into meaningful information for healthcare providers. CHORUS™ generates a weekly email report that alerts clinics to patients with certain conditions who have a scheduled appointment in the coming week and may require close attention. CHORUS™ is a service provided to participating clinics and has been used by AIDS Healthcare Foundation for normal healthcare operations for quality improvement and retention in care in recent years. In the after period of this study, the alert will identify patients with active hepatitis C infection.

Standard of care

Other

CHORUS™ is a service provided to participating clinics and has been used by AIDS Healthcare Foundation for normal healthcare operations for quality improvement and retention in care in recent years. NO alerts identifying patients with active hepatitis C infection will be disseminated.

Primary outcomes

  1. Prescriptions for HCV treatment

    Time frame: End of follow-up, up to 9 months

    Proportion of patients who are prescribed HCV treatment over follow-up, out of patients with a completed visit over follow-up.

Secondary outcomes

  1. HCV RNA viral load tests

    Time frame: End of follow-up, up to 9 months

    Frequency of HCV RNA viral load tests that occur between the first visit over follow-up and the first censoring event

Sponsors and collaborators

Lead sponsor

Epividian

Industry

Collaborators

  • AIDS Healthcare Foundation
  • Gilead Sciences

Registry information

Official study title

Hepatitis C Disease Management: Diagnosis to Treatment Alerts in CHORUS™

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Feb 13, 2023
Registry last updated
Feb 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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