Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients

In a prospective observational study the incidence of Heparin-induced Thrombocytopenia (HIT) Type 2 after orthotopic liver transplantation, associated factors, and hemostaseological findings in thrombocytes and anti-body patterns is going to be investigated.

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Key information

Conditions

Heparin-Induced Thrombocytopenia Liver Transplantation

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Klinikum rechts der Isar der TU München

Munich, D-81675, Germany

About this study

The investigators examined the frequency of anti-PF4/heparin antibodies (IgG/M/A; EIA) and their functional activity (HIPA) in 38 whole organ deceased donor liver transplant recipients. Additionally, demographic, clinical, donor- and recipient-specific parameters and laboratory findings (ALAT, ASAT, cholinesterase) were investigated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

all consecutive liver transplant recipients between 01/2010 and 08/2011 who
were transplanted at our center after allocation of a liver graft via Eurotransplant

Exclusion criteria

patient's refusal to participate in prospective observation

Sponsors and collaborators

Lead sponsor

CHIR-Net

Network

Collaborators

University Medicine Greifswald

Registry information

Official study title

Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients: a Prospective Multivariate Analysis of Prognostic Factors and Haemostaseological Findings

Acronym: HITOLT

Important dates

Study start: 2010
Primary completion: 2011
Study completion: 2011
First posted: Aug 1, 2012
Registry last updated: Aug 1, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed