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OpenTrials
Completed

NCT Number: NCT05610020

Heparin Binding Protein as a Prognostic Biomarker of Sepsis Severity

the aim of the study is to correlate between the severity of sepsis and serum heparin binding protein in the patients admitted to ICU with sepsis., and detect its value as a prognostic biomarker in sepsis

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Key information

Conditions

Sepsis HBP Infections Inflammation Pathologic Processes Pathological Conditions, Signs and Symptoms Systemic Inflammatory Response Syndrome

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Omar Hamdy

Minya, 61511, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult whose age between 20 to70 years old
  • patients suffered from sepsis or septic shock (under the third international consensus definition of sepsis and septic shock)

Exclusion criteria

  • Any pregnancy female
  • Any patient who is Neutropenic secondary to malignancy
  • Patients who is taking immunosuppressive therapy
  • Patients who is suffering fromHematological malignancy

Treatment and study plan

Primary outcomes

  1. Evaluate the level of Heparin binding protein in relation to patient clinical improvement measured by SOFA Score

    Time frame: 72 hours after meeting sepsis ceriteria

    Correlates the change of the level of Heparin binding protein in ng/ml to the clinical improvement of the patients which is measured by SOFA score

Secondary outcomes

  1. Heparin binding protein and mortality

    Time frame: 28 days after meeting sepsis ceriteria

    Correlates the change of the level of Heparin binding protein in ng/ml And how can it is used to predict mortality

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Heparin Binding Protein as a Reliable Prognostic Biomarker for Severity of Sepsis in the Intensive Care Unit

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Nov 8, 2022
Registry last updated
Nov 8, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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