Hemogram Parameter Changes With Sepsis Filter

Hemodiafiltration is initiated in hemodynamically unstable patients in intensive care units. In some patients, additional devices called cytokine filters or sepsis filters are added to remove inflammatory cytokines. Data obtained from hemograms, such as platelet lymphocytosis ratio, are used in the diagnosis or prognosis of many diseases. This study focuses on the change in hemogram rates in patients who received hemofiltration and sepsis filters.

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Key information

Conditions

Platelet Abnormality Blood Platelet Disorders Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Hematologic Diseases Hemic and Lymphatic Diseases Immune System Diseases Immune System Disorder Kidney Diseases Male Urogenital Diseases Renal Failure Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Istinye University

Istanbul, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Data of patients who were monitored in the Intensive Care between January 2020 and December 2022 and who were applied sepsis filters

Exclusion criteria

-Patients who underwent hemodiafiltration with sepsis filter but could not be followed for 72 hours (death, etc.)

Treatment and study plan

Primary outcomes

Platelet lymphocyte ratio change

Time frame: up to 72 hours

Change in platelet lymphocyte ratio measured from hemogram at the beginning (day 0) and the ratio calculated from the sample taken on day 3 in patients undergoing hemodiafiltration with sepsis filter

Secondary outcomes

change in the other ratios derived from complete blood cell count

Time frame: up to 72 hours

Changes in hemogram derivation ratios measured from the hemogram at the beginning (day 0) and the ratio calculated from the sample taken on day 3 in patients who underwent hemodiafiltration with sepsis filter

Sponsors and collaborators

Lead sponsor

Samsun University

Other

Registry information

Official study title

Change in Hemogram-Derived Ratios With Sepsis Filters:A Retrospective Cohort Study in the Intensive Care Unit

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Apr 29, 2025
Registry last updated: Apr 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed