Hematological Disorders in Patients With GI Angiodysplasia

The aim of this study will be to assess the association between GIT angiodysplasia with any hematological disorders as von Willebrand factor and Prognostic value of von Willebrand factor on patient's outcomes as risk of rebleeding and hospital mortality

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Key information

Conditions

GI Bleeding Digestive System Diseases Gastrointestinal Diseases Gastrointestinal Hemorrhage Hemorrhage Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults (above 18 years) and elderly Both genders Admitted to GIT Unit with manifestations of GIT bleeding diagnosed by upper endoscopy and Colonoscopy as angiodyplasia.

Exclusion criteria

other causes of GIT bleeding

Treatment and study plan

Primary outcomes

Correlation between GIT Angiodysplasia and Hematological disorders

Time frame: Baseline
All patients eligible to participate will undergo the following:
- upper endoscopy
- Colonoscopy
- Complete blood count, CRP
- D-Dimer, liver function tests, blood Urea and serum Creatinine
- ECG
- Coagulation profile (aPTT , von Willebrand factor activity &antigen)

Secondary outcomes

Prevelance of different hematological disorders in angiodysplasia patients

Time frame: Baseline
Prognostic value of von Willebrand factor on patient's outcomes as risk of rebleeding and hospital mortality

Time frame: Baseline

Study contacts

Contact information is provided by the study sponsor or research team.

Mennat-allah Alaa Abdelgaber, Resident

CONTACT

[email protected]

+201021789585

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Hematological Disorders in Patients With Gastrointestinal Angiodysplasia

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2027
First posted: Sep 19, 2025
Registry last updated: Sep 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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