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OpenTrials
Completed

NCT Number: NCT01138618

Hematological Clozapine Monitoring With a Point-of-care Device (CHEMPAQ)

Clozapine remain the drug of choice for treatment resistant schizophrenia and up to 60% of patients not responding to other antipsychotics will respond to clozapine. However, the use of clozapine is restricted due to the risk of agranulocytosis and consequently the need for mandatory hematological monitoring. CHEMPAQ XBC is a point-of-care device that can be used in patients home and analyze WBC and granulocytes by a single capillary blood drop. This study aims to investigate whether this new procedure increases the acceptability of clozapine

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Key information

Conditions

Schizophrenia Mental Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Psychiatric Center Roskilde, Greve, Denmark

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Treated with clozapine
  • Compliant with blood monitoring
  • Willing to give informed consent

Exclusion criteria

  • Prior case of agranulocytosis

Treatment and study plan

Venous blod sample

Device

Regular venous blood sample withdrawn from the laboratory

CHEMPAQ

Device

Capillary blood sample analyzed by CHEMPAQ

Primary outcomes

  1. Pain sensation

    Time frame: Monthly for four months

    Pain sensation was measured using a visual analog scale (VAS)

Secondary outcomes

  1. The benefits of CHEMPAQ

    Time frame: Monthly for four months

    Caregivers and patients were asked about the benefits of using CHEMPAQ for hematological clozapine monitoring.

Sponsors and collaborators

Lead sponsor

University of Aarhus

Other

Collaborators

  • Aalborg Psychiatric Hospital

Registry information

Acronym: CHEMPAQ

Important dates

Study start
2010
Primary completion
2010
Study completion
2011
First posted
Jun 7, 2010
Registry last updated
Nov 7, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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