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OpenTrials
Completed

NCT Number: NCT04053465

Heat Acclimation, Hand Cooling Efficacy, and Adaptation Maintenance.

This study had three aims:

1. To determine the impact of consecutive days of exercise on thermoregulation and cardiovascular strain. 2. To determine the efficacy of a hand cooling device to cool individuals throughout a heat acclimation period. 3. To assess the maintenance of thermoregulatory and cardiovascular adaptations derived from heat acclimation during a 25-day intermittent exercise-heat exposure protocol.

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Key information

Conditions

Heat

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

About this study

Participants completed 14 days of exercise heat acclimation in either a hot or cool environment, followed by a heat or cool exercise exposure every 5th day for 25 days. Cardiovascular, thermoregulatory, and perceptual strain were measured throughout exercise each day. Hydration assessment and stress response via blood biomarkers were measured before and after exercise. Aerobic capacity was measured before and after heat acclimation as well as after the intermittent exercise-heat exposure. Hand cooling was implemented periodically during exercise-heat stress visits to determine cooling efficacy before and after heat acclimation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • no chronic health problems
  • no previous history of exertional heat stroke within the past 3 years
  • no history of cardiovascular, metabolic or respiratory disease
  • no current musculoskeletal injury that limits physical activity

Exclusion criteria

  • women
  • exercise less than once per week
  • VO2max < 45 ml/kg/min

Treatment and study plan

Heat acclimation

Other

14 days of aerobic exercise in a hot environment

Exercise in a cool environment

Other

14 days of aerobic exercise in a cool environment

Primary outcomes

  1. Internal Body Temperature

    Time frame: 5 days

    Rectal temperature was assessed five days following measurement at baseline.

Secondary outcomes

  1. Heart Rate

    Time frame: 5 days

    Heart rate was assessed five days following baseline.

Sponsors and collaborators

Lead sponsor

University of Connecticut

Other

Registry information

Official study title

The Effect of Heat Acclimation on Repeated Bouts of Strenuous Heat Stress, Hand Cooling Efficacy, and the Maintenance Thereof.

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Aug 12, 2019
Registry last updated
Feb 27, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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