University of Florida
Gainesville, Florida, 32608, United States
Location status: Recruiting
Recruiting
NCT Number: NCT07634640
Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction
Subjects undergo a gadolinium-based CMR followed by an iron infusion and then a repeat CMR in 72 hours
Recruiting
Interested in participating?
Request InfoKey information
Age range
18 year–85 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Early Phase 1
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- HFpEF
Exclusion criteria
- Renal insufficiency
Treatment and study plan
Ferumoxytol infusion
DrugFerumoxytol infusion followed by cardiac MRI
Primary outcomes
-
detection of inflammation
Time frame: 72 hours
Study contacts
Contact information is provided by the study sponsor or research team.
Ellen C Keeley, MD, MS
CONTACT
Vanessa H Scheuble
CONTACT
Sponsors and collaborators
Lead sponsor
University of Florida
Other
Collaborators
- American Heart Association
Registry information
Official study title
Omega-3 Fatty Acids and Myocardial Inflammation in HFpEF: Preliminary Data and Next Steps
Important dates
- Study start
- 2023
- Primary completion
- 2027
- Study completion
- 2027
- First posted
- Jun 9, 2026
- Registry last updated
- Jun 9, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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