Heart Failure Study: The Atlanta Cardiomyopathy Consortium

Heart failure is a very common cause of hospital admission and there are half a million new cases diagnosed each year in the United States. While some important progress has been made over the last two decades for the treatment of heart failure, there still remains a critical need for further advances in our understanding of this disease in order to significantly improve patient outcomes. Large numbers of heart failure patients need to be studied over time to allow scientists to investigate those factors that influence the responses to therapy.

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Key information

Conditions

Heart Failure Cardiomyopathies Cardiovascular Diseases Heart Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Center for Heart Failure at EUH Midtown, 4th Floor, 550 Peachtree Street, Atlanta, Georgia, United States

About this study

In this study information will be collected on patients with heart failure and their progress and outcomes will be followed over time. The aim is to understand the natural history, risk factors for improvement or progression, and determinants of response to therapy for heart failure. Of interest are many aspects of heart failure including genetic influences, quality of life issues, how individuals cope with feelings about having heart disease, and how they manage their day-to-day symptoms etc.. A database will be created of approximately 1,000 heart failure patients from Emory, Emory University Hospital Midtown, Wesley Woods, Grady, and the VA Medical Center.

This is strictly an observational study and subjects will not be receiving any experimental therapy nor will their routine medical care be affected in any way. Data to be collected includes:

Medical history of the patient
Medical history on the patient's family
Survey data including health behaviors & psychosocial variables
Blood & urine samples
EKG
Six minute Walk Test
Hand grip strength

After collecting data, a variety of statistical tests will be run to analyze factors that influence heart failure patients' responses to treatment. The results of this analysis will be used to optimize therapy for future heart failure patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age: 18 years and over
Sex: Both
Ethnic Origin: All
Diagnosis required to participate: Clinical diagnosis of systolic or diastolic heart failure

Exclusion criteria

Congenital heart disease
Previous heart transplantation
No primary infiltrative disease i.e. amyloidosis

Treatment and study plan

Primary outcomes

Death, Heart Transplant, Left Ventricular Assist Device Implantation

Time frame: 5 years

Secondary outcomes

Hospitalization

Time frame: 30 days

Sponsors and collaborators

Lead sponsor

Emory University

Other

Registry information

Official study title

The Atlanta Cardiomyopathy Consortium

Acronym: TACC

Important dates

Study start: 2007
Primary completion: 2013
Study completion: 2013
First posted: Jan 23, 2008
Registry last updated: Nov 2, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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