Physical Activity and Weight Management Research Laboratory
Pittsburgh, Pennsylvania, 15261, United States
NCT Number: NCT04075279
This is an observational study to examine the cardiovascular mechanisms of increased cardiovascular mortality in those with high activity occupations.
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Notify Me35 year–59 year
Male
Observational
Pittsburgh, Pennsylvania, 15261, United States
The current proposal uses a repeated-measures, within-subject design to address our aims. Twenty male participants will report to the laboratory to provide informed consent, complete baseline assessments, and receive ambulatory monitors. Following this session, each participant will wear physical activity and ambulatory cardiovascular monitors for 7 days, including at least one non-work day and one work day. Characterization of work activity will use physical activity data from self-reported time at work (Specific Aim I). The 24-hour cardiovascular load (HR and BP) and nocturnal HRV will be compared across work and non-work days (Specific Aim II). Lastly, whether fitness level or job strain modify the difference in cardiovascular strain between work vs. non-work days will be evaluated (Specific Aim III).
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 24 hours
We will calculate the average heart rate over each 24 hour period throughout a one week monitoring period.
Time frame: 24 hours
We will calculate the average systolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).
Time frame: approximately 8 hours (sleep time)
We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is root mean square successive differences (RMSSD).
Time frame: 1 week
This physical activity metric of steps per day was calculated as average number of steps during each day type (work versus non-workdays) throughout one week
Time frame: approximately 8 hours (sleep time)
We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is standard deviation of the normal to normal RR intervals (SDNN).
Time frame: approximately 8 hours (sleep time)
We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is low frequency power (LF).
Time frame: approximately 8 hours (sleep time)
We will calculate the average heart rate variability during each night's sleep for a total of one week. The specific HRV variable presented is high frequency power (HF).
Time frame: 1 week
This physical activity metric of minutes of moderate to vigorous physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week
Time frame: 1 week
This physical activity metric of minutes of light physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week
Time frame: 1 week
This physical activity metric of minutes of sedentary time was calculated as average minutes during each day type (work versus non-workdays) throughout one week
Time frame: 1 week
This physical activity metric of minutes of upright time was calculated as average minutes during each day type (work versus non-workdays) throughout one week
Time frame: 24 hours
We will calculate the average diastolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).
University of Pittsburgh
Other
Cardiovascular Mechanisms of the Occupational Physical Activity Health Paradox: 24-hour Physical Activity, Blood Pressure, and Heart Rate
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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