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OpenTrials
Completed

NCT Number: NCT03532919

Heart and Renal Failure in Hip Fracture Surgery

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as well as renal failure noted by Changes in Serum Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

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Key information

Conditions

Hypotension Cardiovascular Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Femoral Fractures Fractures, Bone Heart Injuries Hip Fractures Hip Injuries Kidney Diseases Leg Injuries Male Urogenital Diseases Renal Insufficiency Thoracic Injuries Urogenital Diseases Urologic Diseases Vascular Diseases Wounds and Injuries

Sex eligibility

All sexes

Study type

Observational

Primary location

Sahlgrenska University Hospital

Mölndal, Västra Götaland County, 431 80, Sweden

About this study

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as awell as renal failure noted by Changes in S Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as a step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hip fracture patient to be operated upon Classified as being ASA 3 or more

Exclusion criteria

  • Not forfilling inclusion Criterias

Treatment and study plan

Serum Tropinin

Diagnostic Test

Blodsamples will be taken 4 times from preoperatively to 2 Days postoperatively

Other names: Serum Cystatin C

Primary outcomes

  1. Mortality

    Time frame: 90 days

    post surgery

Secondary outcomes

  1. Serum concentrations of Troponin, NTproBNP, Creatinin and Cystatin C

    Time frame: 90 days

    Relations between values and mortality at 30 and 90 days

Sponsors and collaborators

Lead sponsor

Sahlgrenska University Hospital

Other

Registry information

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
May 22, 2018
Registry last updated
Dec 17, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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