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NCT Number: NCT06923514

Health Literacy, Stress and Quality of Life in Heart Failure Patients

Heart failure is showing a trend of affecting younger individuals. Middle-aged heart failure patients are often the economic backbone of their families. Studies have also pointed out that approximately 38.5% of patients with acute heart failure are re-hospitalized within a year of discharge due to worsening symptoms. Patients with lower health literacy tend to have poorer health outcomes and higher re-hospitalization rates. However, there is limited research on the life and work stress, health literacy, and quality of life of middle-aged heart failure patients. Therefore, this study aims to use machine learning to analyze and predict the correlations between health literacy, stress, and quality of life in heart failure patients.

This research is a cross-sectional correlational study, adopting convenience sampling. The study subjects are cardiology patients aged 18-65 diagnosed with heart failure classified as NYHA II or above by specialists at a regional teaching hospital in northern Taiwan. Data collection took place in the outpatient and inpatient departments of cardiology and cardiothoracic surgery. Structured questionnaires were used for one-on-one interviews, including basic demographic information of heart failure patients, the Chinese version of the European Health Literacy Survey Questionnaire (HLS-EU-Q47), the Chinese version of the Brief Resilience Scale (BRS), the Perceived Stress Scale (PSS), and the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Data will be recorded using Excel, and statistical analysis will be conducted using SPSS version 22. Descriptive statistics such as percentages, means, and standard deviations will be used to describe the demographic and variable distributions. Independent t-tests, ANOVA, and Pearson correlation coefficient will be used to analyze correlations between variables. Machine learning will be employed to analyze and predict quality of life factors in heart failure patients. It is hoped that the results of this study can provide references for nursing practice, help with clinical patient assessment, and improve the quality of care for patients.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Cheng Hsin General Hospital

Taipei, 112, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The study subjects are cardiology patients aged 18-65 diagnosed with heart failure classified as NYHA II or above by specialists at a regional teaching hospital in northern Taiwan

Exclusion criteria

  • 1.severe mental disease.2. terminal stage of other disease such as cancer.

Treatment and study plan

Primary outcomes

  1. Minnesota Living with Heart Failure Questionnaire

    Time frame: one year

    Use the Chinese version of the Minnesota Heart Failure Quality of Life to assess quality of life.

    Use the Chinese version of the Minnesota Heart Failure Quality of Life Questionnaire.There are 21 questions in total, scored from 0 to 5, with a total score of 105. The higher the score, the more serious the impact of the disease on life.

Secondary outcomes

  1. health literacy

    Time frame: one year

    Use the Chinese version of European Health Literacy Survey Questionnaire (HLS-EU-Q) to assess health literacy .

    Use the Chinese version of HLS-EU-Q.There are 47 questions in total. Based on a four-point Likert scale, Total score 0-50. 0-25 means Inadequate,26-33 means Problematic,34-42 means Sufficient,43-50 means Excellent.

Sponsors and collaborators

Lead sponsor

Cheng-Hsin General Hospital

Other

Registry information

Official study title

Using Machine Learning to Analyze the Prediction and Correlation of Health Literacy, Stress and Quality of Life in Heart Failure Patients

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Apr 11, 2025
Registry last updated
Mar 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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