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OpenTrials
Completed

NCT Number: NCT01452087

Health Benefits of Chronic vs. Acute Exercise in Overweight Adults

Compare the effects of single session of exercise vs. chronic exercise training on key risk factors associated with Metabolic Syndrome (e.g., glucose tolerance, blood lipid profile, and blood pressure) in overweight adults.

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Key information

Conditions

Obesity Behavior Body Weight Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Motor Activity Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Substrate Metabolism Laboratory

Ann Arbor, Michigan, 48109, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Body Mass Index: 27-34 kg/m2;
  • Regular exercisers(≥4 days/wk of aerobic exercise;
  • 30-60min/session at moderate and vigorous intensities);
  • Non-exercisers (no regularly planned exercise/physical activity);
  • Women must have regularly occurring menses and must be premenopausal.

Exclusion criteria

  • Pregnant or lactating;
  • Evidence/history of cardiovascular or metabolic disease;
  • Currently taking medications known to affect lipid or glucose metabolism.

Treatment and study plan

Exercise

Other

Subjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).

Primary outcomes

  1. oral glucose tolerance test

    Time frame: 2 hour

Secondary outcomes

  1. Resting Metabolic Rate

    Time frame: 20-30 min

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Registry information

Important dates

Study start
2009
Primary completion
2014
Study completion
2014
First posted
Oct 14, 2011
Registry last updated
Nov 24, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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