International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b)
Dhaka, Capital Region, 1000, Bangladesh
NCT Number: NCT07541742
This study aims to examine how societal and climate changes influence the nutritional status and fish consumption of young women over a 10 year period in southern Bangladesh, and how these factors affect their children's health. A cohort of 240 adolescents first studied in 2017 will be followed to assess changes in their dietary patterns, nutritional status, climate perceptions and mitigation practices, as well as the nutritional status of their children aged 6 months to 5 years.
The study in 2017 sampled 60 adolescent girls in each of four rural communities, plus a semi-rural community around a fish processing plant, representing in total 5 communities. Of these 60 X 5 = 300 girls, the current study follows up the individuals in the rural communities representing a cohort of 240.
Bangladesh faces high rates of adolescent malnutrition, with many girls married before 18 and suffering from chronic nutrient deficiencies. These issues have long-term impacts on health, productivity, and intergenerational well-being. By linking the fisheries and aquaculture sector, a key to Bangladesh's economy with public health and nutrition, this research aims to guide targeted policies for vulnerable coastal communities.
Trial opening soon.
Get Notified5 month–27 year
All sexes
Observational
Dhaka, Capital Region, 1000, Bangladesh
Aquatic foods are fundamental to the Bangladeshi diet, providing nearly two-thirds of total animal protein. Despite this, malnutrition remains a severe public health crisis with a complex etiology. Bangladesh faces a double burden of malnutrition, marked by persistently high rates of micronutrient deficiencies affecting roughly half of both pregnant and non-pregnant women alongside rising levels of overweight and obesity. These challenges are further exacerbated by substantial intrahousehold inequities in this patriarchal society. Disempowerment and early marriage disproportionately expose adolescent girls and young women to inadequate nutrient intake and poor health outcomes, perpetuating an intergenerational cycle of malnutrition. Furthermore, chronic undernutrition and stunting continue to affect a large proportion of children under five.
The problem is particularly acute in coastal communities, where climate change impacts such as salinity intrusion and extreme weather compromise food production and dietary diversity. Understanding and improving the dietary and nutritional status of adolescent girls and young women is therefore essential to breaking the cycle of poor health and ensuring long-term population well-being. Building on a 2017 study conducted with a cohort of 240 adolescents, this research aims to provide longitudinal insights into how nutritional status, female autonomy, aquatic food consumption, and dietary practices have influenced the health and well-being of these women and their children nearly after 10 years.
Hypotheses
Objectives
The study will be conducted in four distinct saline gradient agro-ecological zones across the shrimp-prawn farming regions of southwest Bangladesh, specifically in Fakirhat (Bagerhat District), Dumuria and Paikgacha (Khulna District), and Shyamnagor (Satkhira District).
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
There is no intervention
Time frame: One sampling point between April and August 2026
Eicosapentaenoic acid (EPA) in whole blood (% of total fatty acid)
Time frame: One sampling point between April and August 2026
Docosahexaenoic acid (DHA) in whole blood (% of total fatty acid)
Time frame: One sampling point between April and August 2026
Vitamin D (total 25-hydroxyvitamin D) concentration in blood, nmol/L
Time frame: One sampling point between April and August 2026
Hemoglobin concentration in blood (g/dL)
Time frame: One sampling point between April and August 2026
Ferritin concentration in blood (µg/L)
Time frame: One sampling point between April and August 2026
C-reactive protein concentration in blood (mg/L)
Time frame: One sampling point between April and August 2026
Alpha-1-acid glycoprotein concentration in blood (g/L)
Time frame: One measurement between April and August 2026
Height (cm)
Time frame: One measurement between April and August 2026
Weight (kg)
Time frame: One measurement between April and August 2026
Mid-upper arm circumference (cm)
Time frame: Between April and August 2026
Body mass index (kg/m^2)
Time frame: Between April 2026 to August 2026
Isotope ratios of δ13C and δ15N in hair sample
Time frame: Between April and August 2026
7 days recall, questionnaire
Time frame: Between April and August 2026
Climate change and mitigation practice, questionnaire
Time frame: Between April and August 2026
Women empowerment will be obtained using women empowerment assessment tool, questionnaire.
Time frame: Between April 2026 to August 2026
Dietary pattern by food groups, questionnaire
Time frame: One timepoint between April and August 2026
If a woman has a child aged 6-59 months, the child is assessed for EPA concentration in blood (% of total fatty acids).
Time frame: One measure between April and August 2026
If the woman has a child aged 6 months to 5 years, the child is measured for DHA concentration in blood (% of total fatty acid)
Time frame: April-August 2026
If the woman has a child aged 6 months to 5 years, the child is measured for hemoglobin concentration in blood (g/L)
Time frame: One sampling point between April and August 2026
If the woman has a child aged 6 months to 5 years, ferritin concentration in blood (µg/L), will be measured.
Time frame: One sampling point between April and August 2026
If the woman has a child aged 6 months to 5 years, Vitamin D (total 25-hydroxyvitamin D) concentration in blood, nmol/L will be measured.
Time frame: One sampling point between April and August 2026
If the woman has a child aged 6 months to 5 years, the child's C-reactive protein concentration in blood (mg/L) will be measured.
Time frame: One sampling point between April and August 2026
If the woman has a child aged 6 months to 5 years, alpha-1-acid glycoprotein concentration in blood (g/L) will be measured.
Time frame: Between April and August 2026
If the woman has a child aged 6-59 months, the child's length/height (cm) is measured.
Time frame: April-August 2026
If the women has a child aged 6-59 months, the child is measured for weight (kg)
Time frame: April-August 2026
If the woman has a child aged 6-59 months, the child is measured for MUAC (cm)
Contact information is provided by the study sponsor or research team.
University of Copenhagen
Other
Health and Nutritional Outcomes Among Young Females and Children in Southwest Bangladesh: A Cohort Study
Acronym: AQUAFOOD
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