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OpenTrials
Completed

NCT Number: NCT00753129

Head Elevation in Prone Position

Semi-recumbent position leads to improvement of gas exchange and lung mechanics in patients suffering from ALI or ARDS. Prone positioning leads to similar effects. To date, no data on the combination of these two positioning measures exist. The investigators hypothesize that head elevation in prone position leads to improvement in gas exchange and lung mechanics.

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Key information

Conditions

Gas Exchange Lung Mechanics

Age range

18 year–89 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Dept. of Internal Medicine I, Intensive Care Unit, Medical University of Vienna

Vienna, 1090, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Mechanically ventilated
  • ALI or ARDS
  • No contraindications for prone position

Exclusion criteria

  • Patient < 18 or > 89 years old
  • Pregnancy
  • Elevated intracranial pressure
  • PaO2/FiO2 - ratio < 60
  • ECMO
  • Open abdomen
  • Instable spine
  • Malignant arrhythmias
  • Severe hemodynamic instability

Treatment and study plan

Prone position with head elevation

Procedure

Head elevation of 30° in prone position (Ant-Trendelenburg position of the whole bed)

Primary outcomes

  1. PaO2/FiO2 ratio

    Time frame: Study period (5 hours on 2 consecutive days)

Secondary outcomes

  1. PaCO2, Compliance (Chest wall, lung, respiratory system)

    Time frame: Study period (5 hours on 2 consecutive days)

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Registry information

Official study title

Influence of Head Elevation in Prone Position on Gas Exchange and Lung Mechanics in Patients With ALI/ARDS

Important dates

Study start
2008
Primary completion
2010
Study completion
2010
First posted
Sep 16, 2008
Registry last updated
May 4, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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