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Completed

NCT Number: NCT03678610

Handling Medium for ICSI With Ionomycin and Latrunculin A

Using Latrunculin A and Ionomycin would improve the outcome of ICSI if the handling medium during the ICSI procedure has them.

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Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

18 year–42 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Qena Fertility Center, Qina, Qena Governorate, Egypt

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • indication for ICSI

Exclusion criteria

-

Treatment and study plan

Doing ICSI I a medium supplemented with Ionomycin and Latrunculin A

Other

Ionomycin and Latrunculin A would activate oocyte during ICSI along with cytoskeleton stabilization for a favourable outcomes

Primary outcomes

  1. Fertilization rate

    Time frame: 6 days of culture

Secondary outcomes

  1. Rates of Blastocyst formation and quality

    Time frame: 6 days of culture

    Number of formed blastocysts and blastocysts with good-quality per fertilized oocytes

  2. embryo utilization rate

    Time frame: 6 days of culture

  3. clinical pregnancy rate

    Time frame: three months

  4. ongoing pregnancy rate

    Time frame: 12 weeks

Sponsors and collaborators

Lead sponsor

Ibn Sina Hospital

Other Gov

Collaborators

  • Banoon IVF Center
  • Qena Fertility Center

Registry information

Official study title

Latrunculin A and Ionomycin as a Handling Medium for ICSI

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Sep 19, 2018
Registry last updated
May 7, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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