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NCT Number: NCT06686186

Hainan Community Cognition Cohort

This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up. The research aims to identify risk factors as well as health and social outcomes that are associated with cognitive impairment in elderly populations, and independently develop AI-assisted software and applications for cognitive enhancement and physical rehabilitation training.

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Key information

Conditions

Cognitive Impairment Age Problems Brain Diseases Central Nervous System Diseases Cognition Disorders Cognitive Dysfunction Dementia Mental Disorders Nervous System Diseases Neurocognitive Disorders

Age range

60 year–120 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hainan Medical University

Haikou, Hainan, 571199, China

Location status: Recruiting

Location contact

Jindong Ding Petersen, PHD

CONTACT

[email protected]

+8613256406001

About this study

This is a community-based prospective cohort study in Hainan Province, China. Subjects are individuals aged 60 years and above who have lived in the communities for more than six months and have signed informed consent. The research have been initialed in 2023 and aims to identify the risk factors associated with cognitive impairment, to develop software for cognitive enhancement and physical rehabilitation training. The study includes three steps: first, to conduct cognitive function screening in 16 communities in four districts (Xiuying, Meilan, Longhua, and Qiongshan) of Haikou City and establish a database for the elderly in tropical regions; second, to identify risk factors associated with cognitive impairment in the elderly population; finally, to independently develop a software for cognitive function enhancement and physical rehabilitation training.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

  • Inclusion Criteria:
  • Age 60 years and above
  • Lived in the community for more than 6 months
  • Signed the informed consent form
  • Exclusion Criteria:
  • Cannot complete the survey

Treatment and study plan

No Intervention: Observational Cohort

Other

There were no interventions in our cohort. The subjects of our cohort were and will be followed up at the regular intervals.

Primary outcomes

  1. The prevalence and incidence of cognitive impairment base on the communities

    Time frame: An average of 1 to 2 years

    Mild cognitive impairment was measured using a Chinese version Mini-Mental State Examination, which was collected by questionnaire. The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the cognition outcome.

  2. The prevalence and incidence of dementia using a population-based survey

    Time frame: An average of 1 to 2 years

    Dementia was determined by diagnosis of hospitalization or Clinical Dementia Rating Scale (Montreal Cognitive Assessment, MoCA). The minimum value of the MoCA is 0, and the maximum value is 30, the higher the score, the better the outcome.

    In addition, subtypes of dementia will be based on the specific clinical diagnosis.

  3. The conversion rate of normal to cognitive impairment

    Time frame: An average of 1 to 2 years

    Percentage of enrolled population that convert from normal to cognitive impairment

  4. The conversion rate of cognitive impairment to dementia

    Time frame: An average of 1 to 2 years

    Percentage of enrolled population that convert from cognitive impairment to dementia

Study contacts

Contact information is provided by the study sponsor or research team.

Jindong Ding Petersen, PHD.

CONTACT

[email protected]

089866893772

Sponsors and collaborators

Lead sponsor

Hainan Medical College

Other

Collaborators

  • Fudan University
  • The Second Affiliated Hospital of Hainan Medical University
  • Xuanwu Hospital, Beijing

Registry information

Official study title

A Prospective Cohort of Hainan Community Elderly Population with Cognitive Impairment

Important dates

Study start
2022
Primary completion
2053
Study completion
2053
First posted
Nov 13, 2024
Registry last updated
Nov 13, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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