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Completed

NCT Number: NCT07106437

GREEN CATHeter Lab Study

This study involves the prospective quantification and classification of waste produced during interventional cardiology procedures. For each included case, the total waste generated will be measured in kilograms immediately after completion of the procedure. Waste will be physically sorted and recorded by category in accordance with four predefined waste types: (i) paper and cardboard, (ii) regular waste (i.e., municipal solid waste or general trash), (iii) regulated medical waste (requiring specialized incineration including sharpsafe), and (iv) recyclable plastic. Based on two models ("Basel Model" and "Standard Model"), the study will perform scenario-based calculations to compare the environmental and economic impact of both strategies.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Cardiology, University Heart Center Basel, University Hospital Basel

Basel, 4031, Switzerland

About this study

Interventional cardiology procedures generate substantial amounts of waste, not only medical waste but also large volumes of packaging materials such as paper, cardboard, and plastic. In many hospitals, all procedural waste, regardless of type, is disposed of as medical waste. This practice results in high disposal costs and increased environmental burden, as medical waste requires specialized, energy-intensive incineration and leads to considerable CO₂ emissions. At the University Hospital Basel, waste is systematically separated into categories, enabling structured evaluation of waste streams and environmental impact. Despite growing interest in sustainable healthcare, there is currently a lack of data on the quantity and composition of waste generated per specific procedure type in interventional cardiology. This creates an unmet need to quantify not only how much waste is produced but also to identify which components may be recyclable. this study is to quantify the total amount and type of waste generated during interventional cardiovascular procedures and to contextualize this waste in relation to the average daily waste production of both a Swiss resident and a hospital inpatient. By linking procedural waste generation to familiar population-based benchmarks, This study aims to provide a comprehensible measure of the environmental footprint of each procedure type. Waste will be recorded in kilograms and categorized into four predefined waste streams (paper/cardboard, regular municipal waste, regulated medical waste, and recyclable plastic). To ensure representative and comparable results, at least ten cases for each of the following procedure groups will be included: (i) elective coronary angiography with (ia) or without (ib) percutaneous coronary intervention (PCI), (ii) complex PCI procedures, such as chronic total occlusions (CTO), complex high-risk indicated procedures (CHIP), or interventions performed in patients with cardiogenic shock requiring mechanical support (e.g., Impella), and (iii) structural heart interventions, including TAVI and (iv) TEER of the mitral or tricuspid valves (MitraClip or TriClip).

To assess the broader ecological and financial implications of current waste management practices, two comparative disposal models will be applied. The first, referred to as the "Basel Model", reflects the current institutional practice at the University Hospital Basel, where procedural waste is systematically separated into the four aforementioned categories at the point of care. The second, the "Standard Model", simulates a hypothetical but common practice in many hospitals, in which all waste generated during interventional procedures is disposed of as regulated medical waste, without separation.Based on these two models, the study will perform scenario-based calculations to compare the environmental and economic impact of both strategies.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients undergoing the following interventional procedures:

o Elective diagnostic coronary angiography

  • with PCI
  • without PCI
  • Complex percutaneous coronary interventions (CTO, CHIP, or patients with cardiogenic shock requiring Impella support)
  • Structural heart intervention: TAVI
  • Structural heart interventions: TEER of the mitral or tricuspid valve (MitraClip or TriClip)

Exclusion criteria

  • No exclusion criteria, as no patient-specific data are collected and no modifications to clinical care are introduced

Treatment and study plan

"Basel Model": Measure of total waste after completion of the procedure

Other

For each included case, the total waste generated will be measured in kilograms immediately after completion of the procedure and physically recorded by category in accordance with four predefined waste types: (i) paper and cardboard, (ii) regular waste (i.e., municipal solid waste or general trash), (iii) regulated medical waste (requiring specialized incineration including sharpsafe), and (iv) recyclable plastic

"Standard Model": Measure of total waste after completion of the procedure

Other

Simulation of a hypothetical but common practice in many hospitals, in which all waste generated during interventional procedures is disposed of as regulated medical waste, without separation.

Primary outcomes

  1. Total amount of waste (kilogram) generated per cardiac intervention- procedure type

    Time frame: one time assessment immediately after cardiac intervention

    The waste will be weighed using a certified, hospital-grade scale provided by the in-house hospital pharmacy (Beurer, Typ KS 59, max 20 kg).

  2. Composition of waste (by waste category) generated per cardiac intervention- procedure type

    Time frame: one time assessment immediately after cardiac intervention

    Waste will be physically sorted and recorded by category in accordance with four predefined waste types: (i) paper and cardboard, (ii) regular waste (i.e., municipal solid waste or general trash), (iii) regulated medical waste (requiring specialized incineration including sharpsafe), and (iv) recyclable plastic.

  3. Relation of waste output to the average daily waste production of a Swiss resident (in kilogram)

    Time frame: one time assessment immediately after cardiac intervention

    Relation of waste output generated per cardiac intervention- procedure type to the average daily waste production of a Swiss resident (in kilogram)

  4. Relation of waste output to the average daily waste production of a typical inhospital patient (in kilogram)

    Time frame: one time assessment immediately after cardiac intervention

    Relation of waste output generated per cardiac intervention- procedure type to the average daily waste production of a typical inhospital patient (in kilogram)

Secondary outcomes

  1. Comparison of environmental impact by CO₂ emissions

    Time frame: Postprocedural (one time assessment after cardiac intervention)

    Environmental impact (CO₂ emissions) assuming no waste separation ("Standard model") compared with the structured separation model used at the University Hospital Basel ("Basel model")

  2. Comparison of environmental impact by disposal costs (in Swiss Francs)

    Time frame: Postprocedural (one time assessment after cardiac intervention)

    Environmental impact (disposal costs) assuming no waste separation ("Standard model") compared with the structured separation model used at the University Hospital Basel ("Basel model")

  3. Ecological burden by ReCiPe score

    Time frame: Postprocedural (one time assessment after cardiac intervention)

    Calculation of the ecological burden using ReCiPe score to provide standardized environmental impact score per procedure type (DALY, PDF/m²/yr, $). These values allow for comparison across material types and disposal processes.

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Registry information

Official study title

Assessing Waste and Environmental Impact in Catheterization Laboratories: Results From the GREEN CATHeter Lab Study

Acronym: GREEN-CATH

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Aug 6, 2025
Registry last updated
Mar 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.