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Completed

NCT Number: NCT01686022

Grass Sensitisation and Allergic Rhinitis in Thai Patients

Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.

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Key information

Conditions

Allergy to Grass Pollen Allergic Rhinitis Due to Weed Pollens

Age range

10 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Siriraj Hospital

Bangkoknoi, Bangkok, 10700, Thailand

About this study

To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.

The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Allergic rhinitis patients age 10-50 years old
  • Control: healthy volunteer age 18-50 years old

Exclusion criteria

  • Chronic illness such as cardiovascular diseases, liver diseases
  • History of anaphylaxis
  • Pregnancy

Treatment and study plan

Immunoblot

Other

serum specific IgE binds to grass extract by immunoblot

Sponsors and collaborators

Lead sponsor

Mahidol University

Other

Collaborators

  • National Research Council of Thailand

Registry information

Official study title

The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients

Important dates

Study start
2012
Primary completion
2015
Study completion
2015
First posted
Sep 17, 2012
Registry last updated
Sep 14, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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