Gonorrhea and Chlamydia HIV-infected Men Who Have Sex With Men

This study will estimate the rates of asymptomatic Chlamydia and/or Gonorrhea in the oropharynx, rectum and urethra (urine) of HIV infected men who have sex with men at a specialty care center and compare it to the rates in Douglas County, using nucleic acid amplification tests.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

HIV Infection Bacterial Infections Bacterial Infections and Mycoses Behavior Blood-Borne Infections Chlamydia Chlamydia Infections Chlamydiaceae Infections Communicable Diseases Genital Diseases Gonorrhea Gram-Negative Bacterial Infections HIV Infections Homosexuality Immune System Diseases Immunologic Deficiency Syndromes Infections Lentivirus Infections Neisseriaceae Infections RNA Virus Infections Retroviridae Infections Sexual Behavior Sexuality Sexually Transmitted Diseases Sexually Transmitted Diseases, Bacterial Sexually Transmitted Diseases, Viral Urogenital Diseases Virus Diseases

Age range

19 year and older

Sex eligibility

Male

Study type

Observational

Primary location

University of Nebraska Medical Center, Specialty Care Center

Omaha, Nebraska, 68198-8106, United States

About this study

Hypothesis: Men who have sex with men (MSM) are at higher risk for sexually transmitted diseases. Currently, free testing for sexually transmitted diseases is only being performed in urine samples. Investigators hypothesize that the rates of both gonorrhea and chlamydia will be higher when testing includes more than one anatomical site (rectum and oropharynx).

The aim of the study is to estimate the rates of asymptomatic Chlamydia and/or Gonorrhea in the oropharynx, rectum and urethra (urine) of HIV infected men who have sex with men at the specialty care center of the University of Nebraska Medical Center and compare to the rates in Douglas County, using nucleic acid amplification tests.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

HIV infection
Men with history of sex with men (including transgender and bisexual)
Older than 19 years of age
Asymptomatic at the time of visit.

Exclusion criteria

Active sexually transmitted disease symptoms in the oropharynx.
Recent treatment for Chlamydia or gonorrhea within 3 weeks.
Treatment with antibiotics active for Chlamydia or gonorrhea within the last 2 weeks: doxycycline, quinolones and azithromycin, and cefixime.
Women.
Inability to complete the questionnaire in English or Spanish.

Treatment and study plan

Primary outcomes

Chlamydia or gonorrhea infection

Time frame: one day

Investigators will use nucleic acid amplification tests in urine, rectal and oropharyngeal swab specimens to detect asymptomatic chlamydia and/or gonorrhea infection

Secondary outcomes

accuracy for detecting infection when using one versus 2 versus 3 anatomical sites

Time frame: 1 day

Investigators will compare the proportion of infections detected by using only urine, only rectum, only oropharynx vs. using combined sites (urine and rectum, urine and oropharynx or oropharynx and rectum) vs. using all 3 sites.

Sponsors and collaborators

Lead sponsor

University of Nebraska

Other

Registry information

Official study title

Prevalence of Gonorrhea and Chlamydia Infections in Multiple Anatomical Sites in HIV-infected Men Who Have Sex With Men at an HIV Clinic in Omaha, Nebraska

Important dates

Study start: 2014
Primary completion: 2014
Study completion: 2014
First posted: Dec 24, 2013
Registry last updated: Sep 6, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed