Glycemic Index of Table Grape Varietals

The study aims to investigate the postprandial glycemic responses of healthy individuals when consuming commercially available table grape varietals, compared to a standard amount of glucose. The study also aims to evaluate a new grape varietal, compared to other common table grapes, with regard to glycemic index and metabolic response related to inflammation.

Inclusion criteria

• Healthy men and women
• 21-75 years of age
• BMI range 20-35

Exclusion criteria

• adults unable to consent, individuals who are not yet adults (children), pregnant women, and prisoners.
• BMI of >35 or morbid obesity.
• Diagnosed type 1 or 2 diabetes, fasting blood glucose of >125 mg/dl, or reported use of medications or supplements known to affect glucose metabolism (insulin, sulfonylureas, metformin, glucosidase inhibitors, thiazolidinedione, insulin sensitizers, GLP-1 mimetics).
• Medications known to affect gastrointestinal motility (prokinetic agents such as reglan).
• Renal, liver, pancreatic or cardiovascular disease, uncontrolled hypertension of > 160/90, inflammatory bowel disease, disorders of esophageal and gastrointestinal motility, previous gastric resection or restriction procedures, autoimmune or immunologic disorders, anemia, breastfeeding women
• Food allergy to grapes, or inability to tolerate gluten (celiac disease).
• Poor venous access.
• Smoking, illicit drug use, consuming >7 alcoholic drinks per week.
• Weight gain or loss of > 5 kg within the prior 6 months.
• Unwillingness to adhere to study protocol.