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Completed

NCT Number: NCT01053793

Glycemic Index and Polyphenol Bioavailability of Potatoes

The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.

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Key information

Conditions

Diabetes Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Nutrasource Diagnostic Inc

Guelph, Ontario, N1G 0B4, Canada

About this study

Ten healthy persons will have a fasting blood sample drawn and asked to randomly consume a 50g glucose drink (2 occasions), or 50g carbohydrate equivalent of cooked purple, red, yellow and white potatoes. Further blood samples will be obtained at 15,30, 45, 60, 90, 120, 180, 240 mins. Bloods from the first 2 hours will be analyzed for glucose and insulin to determine the glycemic response. Hourly blood samples will be analyzed for polyphenol to determine the bioavailability of polyphenols from the different potato variety. Urine samples will be collected before ingestion of the food items and again at 4 hours, and will be used to determine polyphenol bioavailability.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy, non-smoker on no medication
  • normal glucose tolerance
  • willing to have a catheter inserted in forearm

Exclusion criteria

  • abnormal glucose tolerance
  • abnormal BMI
  • on medication for a chronic disorder

Treatment and study plan

Glycemic response to different varieties of potatoes

Other

the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard

Other names: Purple potato, Red potato, White potato, Yellow potaot

Primary outcomes

  1. Glycemic response

    Time frame: 2 hrs

Secondary outcomes

  1. Bioavailability of polyphenols from potatoes

    Time frame: 4 hours

Sponsors and collaborators

Lead sponsor

Guelph Food Research Centre

Other Gov

Collaborators

  • Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Registry information

Official study title

A Trial to Measure the Glycemic Index and Polyphenol Bioavailability of Four Different Varieties of Potato.

Acronym: GI

Important dates

Study start
2010
Primary completion
2010
Study completion
2010
First posted
Jan 21, 2010
Registry last updated
Jan 17, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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