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Completed

NCT Number: NCT03521414

Glasgow Coma Scales and General Anesthesia

The study evaluates the general anesthesia management with BIS monitorization in terms of hemodynamic stability, drug concentrations and drug consumption in patients who underwent surgery due to intracranial pathology and who were divided in three different GCS groups.

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Key information

Conditions

Anesthesia Awareness Intraoperative Awareness Intraoperative Complications Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

BIS monitoring is mostly used for anesthesia depth and sedation level follow-up, however it can also be used for monitoring consciousness after resuscitation of cases with acute brain injury and cardiac arrest. It is not always possible to monitor and objectively measure the changes in the level of consciousness in clinical practice. Therefore, device-based methods have been introduced in monitoring the state of consciousness. Bispectral index (BIS) monitoring may be preferred in follow up of the state of consciousness in critical patients such as those with acute brain injury, in terms of ease of use, ability to obtain numerical results and continuous monitoring. BIS monitoring is mostly used for follow up of anesthesia depth and sedation level, while it can also be applied for monitoring state of consciousness following resuscitation in cases with acute brain injury and cardiac arrest.In this study, we aimed to investigate general anesthesia management performed by bispectral index monitoring in patients who underwent surgery due to intracranial pathology and with different Glasgow Coma Scales.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 and 65 years
  • ASA II-III
  • intracranial surgery

Exclusion criteria

  • Patients with additional disease (electrolyte impairment, uremia, etc.),
  • liver and renal failure affecting consciousness level other than intracranial pathology

Treatment and study plan

Bispectral index (BIS) Monitoring

Device

When the patients were taken to the operation table, they were monitored with the BIS. we used sevoflurane drug

Sevoflurane

Drug

we used sevoflurane drug at inoperative

Primary outcomes

  1. BIS, Consumption of the inhalation agents

    Time frame: 200 minutes

    Preoperative, intraoperative and postoperative BIS values were recorded. The total

    amount of opioid consumed was recorded from the infusion pump.

Sponsors and collaborators

Lead sponsor

Trakya University

Other

Registry information

Official study title

The Effect of Glasgow Coma Scales on General Anesthesia in Neurosurgery Patients

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
May 11, 2018
Registry last updated
May 11, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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