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Completed

NCT Number: NCT04658225

Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults

The aim of this study will evaluate the effectiveness of 0.12% chlorhexidine solution as an anti-inflammatory agent and reducing the presence of biofilm in young adults.

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Key information

Conditions

Age Problem Gingival Diseases Gingivitis Infections Mouth Diseases Periodontal Diseases Stomatognathic Diseases

Age range

30 day–30 day

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidade Federal Fluminense

Nova Friburgo, Rio de Janeiro, 28625650, Brazil

About this study

Thirty patients with gingivitis ages 18 to 30 year with a probing depth of at most 3 mm and at least 20 teeth will be selected and evaluate at baseline and after 4 weeks.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Presence of gingivitis
  • Probing depth (PD) with maximum 3 mm
  • Minimum of 20 teeth
  • Age between 18 and 30 years old

Exclusion criteria

  • Patients with periodontal disease (PD ≥ 4mm with clinical attachment loss)
  • Diabetes
  • Osteoporosis
  • Pregnant or lactating females
  • Smokers
  • Users of immune suppressive medication
  • Phenytoin or cyclosporine
  • Calcium channel blockers
  • Antibiotics
  • Nonsteroidal anti-inflammatory drugs
  • HIV+ or AIDS

Treatment and study plan

0.12% chlorhexidine

Procedure

the patients were randomly allocated into two groups of 15 individuals to rinse with antimicrobials twice a day for a period of four weeks. Group A, received 0.12% chlorhexidine antimicrobian in a vial previously identified as solution 1 and group B, received saline solution identified as solution 2.

Other names: Saline Solution

Primary outcomes

  1. Plaque Index

    Time frame: 30 days

    Check the biofilm as Ainano & Bay 1975 index, Higher levels means worse.

Secondary outcomes

  1. Gingival Index

    Time frame: 30 days

    Check the biofilm as Ainano & Bay 1975 index, Higher levels means worse.

Sponsors and collaborators

Lead sponsor

Universidade Federal Fluminense

Other

Registry information

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Dec 8, 2020
Registry last updated
Dec 11, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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