Giardia Induced Fatigue and Functional Gastrointestinal Diseases

A giardiasis outbreak in Bergen has given us the opportunity to approach two basic research questions of national and global importance:

* Studying the pathoimmunology of giardiasis in a natural setting, and following the genetic and immunological responses leading to recovery or persistent disease and sequelae. * Studying the two disease entities FGID and CFS when induced by acute giardiasi and their risk factors. * Interventional cognitive behavioural therapy is the only intervention documented to have significant effect on CFS outcome, and conventional cognitive behavioural therapy will be compared to a psycho-educational programme in the format of a randomised controlled trial.

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Key information

Conditions

Chronic Fatigue Syndrome Chronic Disease Digestive System Diseases Disease Attributes Encephalomyelitis Fatigue Fatigue Syndrome, Chronic Gastrointestinal Diseases Giardiasis Infections Intestinal Diseases Intestinal Diseases, Parasitic Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neuroinflammatory Diseases Neuromuscular Diseases Parasitic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Protozoan Infections Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Frihamnsenteret

Skånevik, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Problems with fatigue of any severity after Giardia infection

Treatment and study plan

Psycoeducation/counseling

Other

2 days of education on mechanisms of illness and coping strategies

Cognitive Behavioural Therapy

Behavioral

4 days intensive training in understanding and behavioural changes

Other names: CBT

Primary outcomes

Improvement minimum 6 points in Chalder Fatigue scale score

Time frame: 6 months

Sponsors and collaborators

Lead sponsor

University of Bergen

Other

Registry information

Official study title

Chronic Fatigue Syndrome and Abdominal Symptoms After Giardia Infection: Clinical Evaluation, Biomarkers, Risk Factors and the Effect of Intervention

Acronym: GIFF

Important dates

Study start: 2009
Primary completion: 2010
Study completion: 2010
First posted: Mar 12, 2009
Registry last updated: Mar 3, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed