Giant Cell Tumor of the Extremities Treated With Surgery and/or Medical Treatment

The purpose of this project is to present the outcomes of patients with giant cell tumor of bone (GCTB) who were treated with surgery and/or medical treatment in a single institution.

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Key information

Conditions

Giant Cell Tumor of Bone Bone Diseases Bone Neoplasms Giant Cell Tumors Musculoskeletal Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Bone Tissue Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue

Sex eligibility

All sexes

Study type

Observational

About this study

The investigators retrospectively review patients treated for GCTB of the extremities between 1990 and 2013 in a single institution. We evaluate the recurrence free survival rate after surgical and medical treatment of patients with GCTB of the extremities to determine the influence of the surgical approach, denosumab therapy, local tumor presentation, and demographic factors on the risk of recurrence.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

giant cell tumors of the extremities

Exclusion criteria

giant cell tumors of the spine and pelvis

Treatment and study plan

curettage and resection

Procedure

the investigators analyzed patients with giant cell tumor of bone who underwent curettage or resection with or without denosumab administration

Other names: denosumab

Primary outcomes

local recurrence rate after surgical and medical treatment

Time frame: within the first 36 months after surgery

Sponsors and collaborators

Lead sponsor

Istituto Ortopedico Rizzoli

Other

Registry information

Official study title

Il Tumore a Cellule Giganti Delle estermità

Acronym: GCTLIMBS

Important dates

Study start: 2016
Primary completion: 2016
Study completion: 2016
First posted: Dec 19, 2016
Registry last updated: Dec 22, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed