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Completed

NCT Number: NCT02413112

Get in Shape in the Team Research: Porukalla Kuntoon Tutkimus

It is well accepted that physical activity in the form of resistance training produces a wide variety of neuromuscular-skeletal and health benefits. It is recommended in Finland that older individuals (over 65yr) should perform resistance training twice per week.

Unfortunately, only approx. 5% of older individuals fulfill this recommendation. As Finnish society grows ever older, research should focus on the specific needs of this group and how to improve participation in physical activity, which may ultimately lead to modification of physical activity recommendations - resistance training recommendations are currently the same for young and older adults and do not include specific recommendations on the type of resistance training. However, these recommendations appear to have been developed for "best possible" improvements in maximum strength and muscle size.

Therefore, it is of great importance to identify the number of resistance training sessions per week required to induce improvements in physical fitness, metabolic and bone health status, and importantly the reasons for adherence to/drop-out of resistance training interventions (e.g. motivation to train) in a multi-discipline study. This knowledge would benefit policy makers to update current recommendations for resistance training and to devise strategies to advise realistic targets for resistance training in the older, particularly the less-educated, age group (e.g. TELI-strategy for 2020).

The present study will include a 12-month resistance training intervention with a 12-month follow-up period. Interviews and questionnaires will assess psychological/sociological data and will be collected from both drop-out subjects and those that complete the intervention. Neuromuscular performance and functional capacity will be tested using conventional methods, along with body composition, bone density, and blood tests for metabolic markers of health. Diet and other physical activity will be controlled throughout the intervention period. Measurements are to be performed every 3 months.

It is expected that 5 international peer-reviewed articles will be published in 2016-2017. The data will be presented at international and national conferences in 2015-2017. Finally, results of the entire research will be published in national peer-reviewed journals (e.g. The Age Institute's "Raportteja"). All subjects will be invited to attend an information meeting where group results will be presented and explained.

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Key information

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI<37
  • Does not smoke
  • Able to perform all tests and exercises
  • Free from episodes during physical activity

Exclusion criteria

  • BMI>37
  • Use of waling aids
  • Previous testosterone-altering treatment, e.g. in cancer treatment or hypogonadism
  • Serious cardiovascular disease that may lead to complications during exercise
  • Use of pharmaceuticals that affect neuromuscular or endocrine systems
  • Regular endurance training>3hr per week
  • Resistance training experience

Treatment and study plan

Resistance training

Behavioral

Whole-body resistance training in the University gym that is supervised by researchers.

Training once per week, Training twice per week, Training thrice per week.

Primary outcomes

  1. Force production (Isometric and dynamic maximum strength tests of lower limbs)

    Time frame: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

    Isometric and dynamic maximum strength tests of lower limbs

  2. Muscle hypertrophy (Cross-sectional area of quadriceps and triceps surae muscles)

    Time frame: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

    Cross-sectional area of quadriceps and triceps surae muscles

Secondary outcomes

  1. Body composition (DXA scanning)

    Time frame: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

    for body fat and fat-free mass

  2. Blood count

    Time frame: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

    Basic blood count

  3. Oral glucose tolerance test

    Time frame: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

    Oral glucose tolerance test assessed for glucose and insulin concentrations

  4. Basal hormone concentrations

    Time frame: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

    Basal hormone concentrations from serum

Sponsors and collaborators

Lead sponsor

University of Jyvaskyla

Other

Registry information

Official study title

Minimum Resistance Training Frequency: Effect on Motivation and Adherence to Train, Overall Health Status and Neuromuscular Performance

Acronym: PoKu

Important dates

Study start
2015
Primary completion
2015
Study completion
2016
First posted
Apr 9, 2015
Registry last updated
Oct 25, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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