Genetic Testing for All Breast Cancer Patients (GET FACTS)

• The research study procedures include screening for eligibility and study interventions including evaluations and follow up visits
• After receiving genetic testing, participants will be placed into one of two counseling methodology groups:

• Standard genetic counseling: Standard of care discussion
• Quantitative genetic counseling: Discussion is guided by tables and graphs.
• Participants will be on the research study for up to six months, with an optional extension to two years.
• It is expected that about 450 people will participate.
• This research study is a Feasibility Study, which is the first-time investigators are examining this form of genetic counseling.
• This is a randomized study. Randomization means being put into a group by chance. It is like flipping a coin. Neither the participant nor the Investigator will choose the group the participant is assigned to.

Inclusion criteria

• Patients with a new breast cancer diagnosis (invasive or in-situ) considering genetic testing
• Patients with good understanding of written and spoken English
• Patients with apparent cognitive capacity to make surgical decisions for themselves
• Patients who are medically cleared for surgery
• Patients must be at least age 18 but under 79

Exclusion criteria

• Previous breast cancer diagnosis (invasive or DCIS)
• Metastatic breast cancer
• Patients who have received prior broad-based panel testing (prior BRCA1/2 testing with negative results allowed)
• Bilateral breast cancer
• Known medical or surgical contraindication to contralateral mastectomy
• Hematologic malignancy necessitating skin biopsy/fibroblast culture for germline genetic testing malignancy other than cervical cis or basal or squamous cell skin cancers.