Genetic Markers of Diabetic Ulcers and Personalized Treatment Targets Research

Inclusion criteria

• 1) Subjects who voluntarily participate in this clinical study and sign informed consent;
• 2) Patients with type 2 diabetes and diabetic ulcers;
• 3) Disease duration ≥ 10 years or age ≥ 55 years at enrollment;
• 4) Inpatient or outpatient who can be monitored by the same investigating team throughout the duration of the study.

Exclusion criteria

• 1) Severe vascular occlusion or impairment;
• 2) Patients with congenital heart disease, aortic dissection, or other severe cardiovascular diseases;
• 3) Patients with ulcers caused by factors other than diabetes;
• 4) Patients with severe liver and kidney dysfunction or serious neurological impairment.