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OpenTrials
Completed

NCT Number: NCT00856921

Genetic Evaluation of AAAS Gene in Early-Onset Achalasia and Alacrima Patients

The AAAS gene has been known to cause achalasia, alacrima, adrenal abnormalities and a progressive neurological syndrome. A considerable proportion of achalasia patients have been known to show alacrima (decreased secretion of tears). However, the genetic mechanism between achalasia and alacrima has not been defined yet. The investigators postulated that some proportions of early-onset achalasia could be correlated with AAAS gene; thus, the investigators aimed to investigate the relationship between the AAAS gene and early-onset achalasia.

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Key information

Conditions

Achalasia Alacrima Deglutition Disorders Digestive System Diseases Esophageal Achalasia Esophageal Diseases Esophageal Motility Disorders Gastrointestinal Diseases

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • early age onset
  • primary achalasia patient
  • less than 35 years old

Exclusion criteria

  • secondary achalasia patients

Treatment and study plan

Primary outcomes

  1. Genetic relationship between achalasia and AAAS gene

Sponsors and collaborators

Lead sponsor

Asan Medical Center

Other

Registry information

Official study title

To Find Out the Genetic Relationship Between the Early-Onset Achalasia and AAAS Gene

Acronym: AAAS

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Mar 6, 2009
Registry last updated
Mar 6, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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