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OpenTrials
Completed

NCT Number: NCT02749786

Genetic Basis of Rosacea Study (Control)

Rosacea is a common disease characterized by inflammation and vascular abnormalities of the facial skin and ocular surface. It it considered to be a syndrome encompassing various combinations of cutaneous signs including flushing, erythema, telangiectasia, papules, edema, ocular lesions, and rhinophyma. The exact etiology of cutaneous rosacea is unknown but is characterized by persistent vasodilation, increased vascular permeability, and vascular hyper-reactivity of the microcirculation of the central part of the face. The purpose of this study is to develop gene expression profiles of papulopustular rosacea compared to those of normal skin. The investigator hopes to better understand the abnormal gene functions that might contribute to this condition. This understanding may lead to the development of additional and better treatments for rosacea.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Stanford Dermatology

Redwood City, California, 94603, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

include:

  • Fitzpatrick skin type II or III
  • Age greater than or equal to 18 years
  • Individuals without a history of rosacea

Exclusion criteria

include:

  • Women who are pregnant or lactating
  • Use of topical prescription medications or procedures to the face within one month of enrollment
  • Skin conditions that might interfere with interpretation of procedure results (at the discretion of the investigator)

Treatment and study plan

Skin biopsy

Other

Skin biopsies will be performed via the Keys punch technique from normal facial skin.

Primary outcomes

  1. Gene expression profile of papulopustular rosacea compared to normal skin and skin from individuals without rosacea.

    Time frame: Up to 2 years

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Registry information

Official study title

Expansion Arm of Papulopustular Rosacea Gene Expression Profiling to Include Normal Individuals as Anatomic Site Specific Controls

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Apr 25, 2016
Registry last updated
Sep 26, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.