Genetic Basis of Rosacea

Eligibility Criteria for Rosacea Group:

Inclusion criteria

for rosacea participants:

• Clinical signs and symptoms of rosacea (papulopustular or erythrotelangiectatic subtypes) present at enrollment as determined by the investigator
• All four grandparents of European descent
• Fitzpatrick skin type I or II
• Age 18 years or older

Exclusion criteria

for rosacea participants:

• Unable or unwilling to provide written informed consent
• Concomitant facial or medical condition that obscures diagnosis of rosacea (such as malar erythema from lupus erythematosus)
• Acne vulgaris
• Unable or unwilling to provide peripheral blood sample (a few teaspoons)
• Inability for investigator to verify rosacea diagnosis on clinical examination due to rosacea treatment(s) leading to complete lack of signs and symptoms (such prior laser treatments, systemic tetracycline usage, etc.)
• Use of topical prescription medications or procedures to the face within one month of enrollment
• Women who are pregnant or lactating

Eligibility Criteria for Non-Rosacea Group:

Inclusion criteria

for control participants:

• No history of rosacea
• No clinical signs or symptoms of rosacea
• No family history of rosacea
• All four grandparents of European descent
• Fitzpatrick skin type I or II
• Age 18 years or older

Exclusion criteria

for control participants:

• Unable or unwilling to provide written informed consent
• Acne vulgaris
• Unable or unwilling to provide peripheral blood sample (a few teaspoons)
• Women who are pregnant or lactating
• Use of topical prescription medications or procedures to the face within one month of enrollment
• Skin conditions that might interfere with interpretation of procedure results (at the discretion of the investigator)