Genetic Basis of Pacing-induced Cardiomyopathy

The purpose of this study is to collect a saliva sample from patients with a pacemaker to study genes involved in cardiomyopathy, a condition where the heart muscle is abnormal.

Completed

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Key information

Conditions

Pacemaker, Artificial Cardiomyopathies Cardiovascular Diseases Heart Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Robert Packer Hospital

Sayre, Pennsylvania, 18840, United States

About this study

DNA will be extracted from the saliva to test for changes in genes related to cardiomyopathy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who have been assessed for cardiomyopathy

Exclusion criteria

Patients who do not have adequate follow up care to determine if they do or do not have cardiomyopathy

Treatment and study plan

Saliva Sample

Other

Extract sample of saliva only once

Primary outcomes

Number of participants with genotype frequency

Time frame: through study completion, an average of 1 year

Number of participants with genotype frequency based on genetic testing of saliva samples

Sponsors and collaborators

Lead sponsor

The Guthrie Clinic

Other

Registry information

Important dates

Study start: 2017
Primary completion: 2025
Study completion: 2025
First posted: Oct 23, 2017
Registry last updated: Jun 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed