Generic Database of Moderate Preterm Infants

The Moderate Preterm Registry is a registry of moderate preterm infants (29-33 weeks gestational age) born alive in NICHD Neonatal Research Network (NRN) centers. The purpose is to collect baseline and outcome data in a uniform manner on a cohort of infants.

The registry collects observational baseline data on both mothers and infants, and the therapies used and outcomes of the infants. The information collected is not specific to a disease or treatment (i.e., it is "generic"). Baseline data is collected soon after admission to the NICU; outcome data is collected at the time of death or discharge from the hospital. The data collected includes information on:

• Demographics of mother and infant
• Mother's health (e.g., pregnancy history and complications)
• Labor and deliver (e.g., rupture of the membranes, steroids and antibiotics given, mode of delivery)
• Infant's health (gestational age, Apgar scores, weight, length, delivery room resuscitation, respiratory support, etc.)
• Infant's medical outcome (heart, lung, nervous system, gastrointestinal system, hearing, and vision, known infections, and major malformations/syndromes, and mortality or number of days hospitalized).

These data are used: to examine associations between baseline characteristics, treatments, and outcomes; to track trends in incidences of disease and effectiveness of therapies; and to identify questions requiring additional in-depth research.

Informed Consent: As required by local IRBs.

Inclusion criteria

• Gestational age 29-33 weeks
• Inborn infants and outborn infants admitted by 72 hours.

Exclusion criteria

• None