Gene - Exercise Research Study

The investigators hypothesize that the degree to which older generally healthy but sedentary men and women improve a number of cardiovascular (CV) disease risk factors with 6 months of highly-standardized endurance exercise training will be a function of common genetic variations in candidate genes.

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Key information

Conditions

Cardiovascular Disease Risk Factors Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases

Age range

50 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Maryland Dept of Kinesiology

College Park, Maryland, 20742-2611, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

generally healthy
free from CV disease
ability to undergo exercise training

Exclusion criteria

previous history of CV disease

Treatment and study plan

Endurance Exercise Training

Behavioral

Primary outcomes

Cardiovascular Disease Risk Factors

Time frame: ~9 months

Sponsors and collaborators

Lead sponsor

University of Maryland, College Park

Other

Collaborators

University of Maryland, Baltimore
University of Pittsburgh

Registry information

Official study title

Impact of Common Genetic Polymorphisms on CV Disease Risk Factor Changes With Endurance Exercise Training

Acronym: GERS

Important dates

Study start: 1998
Primary completion: 2004
First posted: Sep 14, 2009
Registry last updated: Apr 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed