Gender-specific Associations Between Quality of Life and Leukocyte Telomere Length

Quality of life (QoL) is an important factor for successful aging. Telomere length is an indicator of cellular aging and cumulative biological stress and is thus related to health status and survival. However, the relationship between QoL and telomere length has not yet been examined. In this study we investigated the relationship between leukocyte telomere length (LTL) and QoL.

However, the relationship between overall QoL and LTL has not previously been investigated. Therefore, this study was conducted to examine the relationship between LTL and QoL. QoL was measured by the Korean version of the 36-item short-form health survey (SF-36), which is a multidimensional scale consisting of subjective evaluation.

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Key information

Conditions

Apparently Healthy People Aged 55 and Over

Age range

55 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

married couple
apparently healthy subjects above 55 years

Exclusion criteria

Subjects who had experienced hormone therapy
Subjects who had been diagnosed with dementia, Parkinson's disease, stroke, ischemic heart disease, congestive heart failure, arrhythmia, depression, cancer, thyroid disorders, or chronic renal disease

Treatment and study plan

Quality of life

Other

Quality of life which was measured by the Korean version of the 36-item short-form health survey (SF-36)

Primary outcomes

leukocyte telomere length

Time frame: 8months

Leukocyte telomere length was measured as telomere repeat copy number relative to single gene copy number by quantitative real-time PCR

Sponsors and collaborators

Lead sponsor

Jung-Ha Kim

Other

Registry information

Official study title

Gender-specific Associations Between Quality of Life and Leukocyte Telomere Length: A Cross-sectional Study

Important dates

Study start: 2013
Primary completion: 2014
Study completion: 2014
First posted: May 12, 2017
Registry last updated: May 12, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.