Skip to main content
OpenTrials
Completed

NCT Number: NCT00192842

Gemcitabine With Curcumin for Pancreatic Cancer

The study hypotheasis is that curcumin, a natural compound with a potent antiproliferative effect, can improve the efficacy of the standard chemotherapy gemcitabine in patients with advanced pancreatic cancer. That is why the patients are given a daily oral dose of 8 gr of curcumin along the chemotherapeutic protocol of weekly gemcitabine.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pancreatic Cancer Carcinoma Digestive System Diseases Digestive System Neoplasms Endocrine Gland Neoplasms Endocrine System Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Pancreatic Diseases Pancreatic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • locally advanced or metastatic adenocarcinoma of the pancreas
  • no prior chemotherapy
  • performance status 0-2
  • adequate hematology and chemistry

Exclusion criteria

  • serious concurrent medical condition

Treatment and study plan

curcumin (+ gemcitabine)

Drug

Primary outcomes

  1. time to tumor progression

Secondary outcomes

  1. response rate

  2. survival

  3. clinical benefit

  4. toxicity

Sponsors and collaborators

Lead sponsor

Rambam Health Care Campus

Other

Registry information

Official study title

Phase II Trial of Gemcitabine and Curcumin in Patients With Advanced Pancreatic Cancer

Important dates

Study start
2004
Primary completion
2007
Study completion
2010
First posted
Sep 19, 2005
Registry last updated
Sep 22, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.