Gastric Cancer Surgery in Elderly Patients

Gastric cancer is most frequent after the fifth decade of life. Surgical risk is higher in aged population because of general health condition may affect the postoperative result. Aim of the study was to identify risk factors for post-operative mortality in octogenarian patients who underwent surgery for gastric cancer.

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Key information

Conditions

Gastric Cancer Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Neoplasms Neoplasms by Site Stomach Diseases Stomach Neoplasms

Age range

80 year–90 year

Sex eligibility

All sexes

Study type

Observational

About this study

236 patients (181: 80-85 years old and 55: >85 years old) underwent surgery for gastric cancer at the Sant'Orsola-Malpighi University Hospital in Bologna between 2010 and 2015. The variables of the two groups of patients were compared.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with histologically confirmed primary gastric cancer submitted to surgical treatment;
Age > 80 years.

Exclusion criteria

Patients with histologically confirmed primary gastric cancer submitted to surgical treatment and age < 80 years;
Patients with histologically diagnosis of other neoplastic and non-neoplastic diseases submitted to surgical treatment.

Treatment and study plan

Gastric resection

Procedure

Partial gastrectomy with jejunal anastomosis," "total gastrectomy," "gastroenterostomy without gastrectomy" or "other" (palliative surgery).

Primary outcomes

Post-operative mortality In-hospital mortality was defined that occurred during hospitalization up to 90 days excluded post-operative mortality. Postoperative mortality

Time frame: Up to 90-days

mortality occurred up to 90 days from surgery

Secondary outcomes

Overall survival

Time frame: Up to 5-years

Overall survival was defined as the time from the date of surgery to patient death (including surgery-associated death or hospital death), or the date of last available information concerning vital status.

Sponsors and collaborators

Lead sponsor

University of Bologna

Other

Registry information

Official study title

Post-Operative Outcomes And Predictors Of Mortality After Gastric Cancer Surgery In The Very Elderly Patients

Acronym: GCSEP

Important dates

Study start: 2010
Primary completion: 2015
Study completion: 2018
First posted: Dec 17, 2018
Registry last updated: Dec 17, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed