Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07565896

Gardening for Health for Cancer Survivors

This study is testing whether a gardening and nutrition program can improve well-being in people who have had cancer. Many cancer survivors continue to experience challenges after treatment, including changes in appetite, nutrition, stress, and quality of life. Programs that combine healthy eating, physical activity, and social connection may help address these issues.

In this study, participants will take part in a 6-week, in-person program called Gardening for Health. The program includes weekly group sessions held at a garden at the University of Vermont Medical Center. Each session lasts about two hours and includes hands-on gardening activities, nutrition education, cooking demonstrations, and guided wellness practices such as mindfulness and light movement. Participants will also receive educational materials to support healthy eating and gardening at home.

The main goal of the study is to determine whether this program is feasible and acceptable for cancer survivors, meaning whether people are willing to participate, attend sessions, and find the program helpful and satisfying. The study will also explore whether participation is associated with improvements in quality of life, stress, sense of belonging, and nutrition-related behaviours.

Participants will complete questionnaires before starting the program and again after the 6-week program ends. These surveys will ask about overall health, stress levels, social connection, and lifestyle habits.

The researchers hypothesize that participation in the Gardening for Health program will be feasible and well-received by cancer survivors, and that it may lead to improvements in quality of life, reduced stress, and increased feelings of connection and well-being.

This is a single-group study, all participants receive the intervention and there is no comparison group. The results will help determine whether this type of program should be studied further in larger trials.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Quality of Life Lifestyle Intervention

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This is a prospective, single-center, single-arm feasibility study designed to evaluate a structured gardening and nutrition-based intervention, among adult cancer survivors. The study will enroll approximately 15 participants at the University of Vermont Cancer Center.

Cancer survivors frequently experience persistent challenges following treatment, including nutritional deficits, altered taste and appetite, reduced physical activity, psychosocial stress, and decreased quality of life. Prior research has demonstrated that multi-component lifestyle interventions, may improve dietary intake, physical functioning, and psychosocial outcomes. Building on this evidence and prior pilot work conducted at the University of Vermont Medical Center, this study evaluates an adapted, short-duration gardening and nutrition intervention tailored specifically for cancer survivors.

The intervention consists of six weekly, in-person sessions delivered over approximately six weeks in a rooftop garden setting. Each session is approximately two hours in duration and is led by a multidisciplinary team. The intervention integrates hands-on gardening activities, nutrition education, culinary instruction, and experiential components such as mindfulness, light physical activity, and nature-based engagement.

The primary objective is to evaluate feasibility and acceptability of the intervention, assessed through recruitment, retention, attendance, and participant satisfaction. Secondary objectives include assessing pre- to post-intervention changes in psychosocial outcomes, including health-related quality of life, perceived stress, and sense of belonging, as well as exploratory changes in nutrition-related knowledge and behaviors.

Participants will complete self-report assessments at baseline (prior to intervention initiation) and immediately following completion of the intervention. Qualitative feedback collected through post-intervention surveys will be analyzed to characterize participant experience and perceived impact.

This study is not powered to detect statistically significant differences in outcomes but is intended to generate preliminary data on feasibility, acceptability, and potential signals of efficacy to inform the design of future controlled trials.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 years or older
  • Self-reported current or prior diagnosis of cancer
  • Self-identifies as a cancer survivor
  • Ability to read, write, and speak English

Exclusion criteria

  • Currently significantly immunosuppressed

Treatment and study plan

Gardening and Nutrition Intervention

Behavioral

The intervention is a structured, six-week, in-person gardening and nutrition-based program delivered at the University of Vermont Medical Center rooftop garden. Participants will attend one session per week, each approximately two hours in duration, for a total of six sessions. The program is led by a multidisciplinary team.

Each session integrates hands-on gardening activities (e.g., planting, garden maintenance, harvesting), nutrition education (e.g., dietary fiber, hydration, anti-inflammatory foods), and culinary instruction focused on preparing healthy meals. The program also incorporates experiential components such as mindfulness practices, light physical activity, and engagement with natural outdoor environments.

Participants will receive educational materials, including a gardening and nutrition curriculum packet, to support continued application of skills outside of the sessions.

Primary outcomes

  1. Acceptability of the Gardening and Nutrition Intervention

    Time frame: At 6 weeks (post-intervention)

    Acceptability will be assessed using a post-intervention participant satisfaction survey. Measures will include participant-reported satisfaction with the program, perceived usefulness of the intervention components, and willingness to recommend the program to others. Responses will be summarized descriptively to evaluate overall participant satisfaction and perceived value of the intervention.

    Responses will be scored on a 5-point Likert scale (1 = strongly disagree to 5 = strongly agree).

  2. Recruitment Rate

    Time frame: At 6 weeks (post-intervention)

    Recruitment rate will be defined as the number of participants enrolled divided by the number of eligible participants who expressed interest in the study during the recruitment period.

    Unit of Measure: Percentage (%) Time Frame: During study enrollment period (up to 6 weeks)

  3. Retention Rate

    Time frame: At 6 weeks (post-intervention)

    Retention rate will be defined as the proportion of enrolled participants who complete the full intervention and post-intervention assessments (T2).

    Unit of Measure: Percentage (%)

  4. Session Attendance

    Time frame: During the 6-week intervention period

    Session attendance will be defined as the number of intervention sessions attended by each participant out of 6 total sessions. Attendance will be summarized as both the mean number of sessions attended and the proportion of sessions attended.

    Unit of Measure: Number of sessions (0-6) and Percentage (%)

  5. Assessment Completion Rate

    Time frame: At 6 weeks (post-intervention)

    Assessment completion will be defined as the proportion of participants who complete all required baseline (T1) and post-intervention (T2) questionnaires.

    Unit of Measure: Percentage (%)

Secondary outcomes

  1. Change in Health-Related Quality of Life (SF-36)

    Time frame: Baseline to 6 weeks

    Health-related quality of life will be assessed using the 36-Item Short Form Health Survey (SF-36). The SF-36 evaluates eight domains, including physical functioning, role limitations, emotional well-being, social functioning, pain, energy, and general health. Scores will be calculated according to standard scoring procedures, and changes from baseline to post-intervention will be analyzed.

    Each domain score is transformed to a 0 to 100 scale, with higher scores indicating better health-related quality of life.

    The outcome will be defined as the change in SF-36 domain scores from baseline (T1) to post-intervention (T2).

  2. Change in Perceived Stress (Perceived Stress Scale)

    Time frame: Baseline to 6 weeks

    Perceived stress will be assessed using the 10-item Perceived Stress Scale (PSS). The PSS measures the degree to which situations in one's life are perceived as stressful over the past month. The PSS includes 10 items rated on a Likert scale from 0 (never) to 4 (very often), with total scores ranging from 0 to 40. Total scores will be calculated, and changes from baseline to post-intervention will be evaluated. Higher scores indicate greater perceived stress (worse outcome).

    The outcome will be defined as the change in total PSS score from baseline (T1) to post-intervention (T2).

  3. Change in Sense of Belonging (General Belongingness Scale)

    Time frame: Baseline to 6 weeks

    Sense of belonging will be assessed using the General Belongingness Scale (GBS), which measures feelings of social inclusion and rejection. The GBS consists of 12 items rated on a Likert scale from 1 (strongly disagree) to 7 (strongly agree), with total scores ranging from 12 to 84. Total and subscale scores will be calculated, and changes from baseline to post-intervention will be analyzed.

    Higher scores indicate greater sense of belonging (better outcome).

Study contacts

Contact information is provided by the study sponsor or research team.

Randall F Holcombe, MD

CONTACT

[email protected]

1 (802) 656-2021

Sponsors and collaborators

Lead sponsor

University of Vermont Medical Center

Other

Registry information

Official study title

Gardening for Health for Cancer Survivors (G4H-CS)

Acronym: G4H-CS

Important dates

Study start
2028
Primary completion
2042
Study completion
2042
First posted
May 4, 2026
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.