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Completed

NCT Number: NCT07015710

Gamma Knife Radiosurgery on Tectal Plate Gliomas

This study aimed to assess the impact of gamma knife radiosurgery on tectal plate gliomas (TPGs).

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Key information

Age range

5 year–55 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Al-Azhar University (Damietta)

Damietta, 0000-0001-6746-3024, Egypt

About this study

Tectal plate gliomas (TPGs) represent a subset of brainstem gliomas that are predominantly slow-growing, low-grade tumors and rarely produce neurological deficits.

Viable options include biopsy and monitoring with serial neuroimaging, surgical resection, radiotherapy (either early following surgery or late on evidence of disease progression), chemotherapy, and stereotactic radiosurgery (SRS).

SRS using Gamma Knife radiosurgery (GKRS) has been identified in small case series as a safe and promising approach for managing TPGs that necessitate intervention beyond mere observation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age from 5 to 55 years.
  • Both sexes.
  • Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Exclusion criteria

  • High-grade glioma.
  • Tumor extension beyond the tectal region.

Treatment and study plan

Gamma Knife Radiosurgery

Procedure

Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).

Primary outcomes

  1. Incidence of response

    Time frame: One year post-procedure

    Incidence of response was recorded.

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Impact of Gamma Knife Radiosurgery on Tectal Plate Gliomas

Important dates

Study start
2021
Primary completion
2024
Study completion
2024
First posted
Jun 11, 2025
Registry last updated
Jun 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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