Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT07419984

Gamified Neurology Grand Rounds

The goal of this research study is to learn if a new, game-based way of teaching neurology grand rounds (called "gamified teaching") works better than the traditional lecture-based format for neurology residents. It will also test whether using wristbands that measure stress and attention can help teachers adjust their pace in real time, and whether earning digital achievement badges motivates residents to keep learning.

The main questions it aims to answer are:

Does gamified teaching help residents remember key information longer (up to 3 months) compared to traditional teaching?

Does it improve how efficiently residents make clinical decisions (for example, ordering the right tests without unnecessary extras)?

Do teachers who receive real-time feedback from the wristbands deliver sessions that feel less tiring and more engaging to residents?

Do residents find the digital badges useful, and do they encourage more self-study?

Researchers will compare the gamified teaching method to the traditional lecture method. Each resident will experience both formats at different times (a "crossover" design). An additional small group will only receive the traditional format to help rule out other factors.

Participants will:

Take part in eight neurology grand rounds sessions over two 4-week periods (four sessions per period)

Wear a research wristband during each session to measure their physiological responses (skin activity and heart rate)

Complete short quizzes right after each session and again three months later

Fill out brief questionnaires about their learning experience and motivation

Use a custom interactive platform during the gamified sessions to work in teams, make clinical decisions, and earn digital badges

All information collected will be kept confidential, and participants may leave the study at any time without any impact on their residency evaluations.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Education, Medical Grand Rounds

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

West China Hospital of Sichuan University

Chengdu, Sichuan, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Currently enrolled in postgraduate year 1 (PGY1), PGY2, or PGY3 of an accredited neurology residency program
  • No prior formal participation in structured gamified neurology teaching programs focused on clinical reasoning
  • Able to attend all eight scheduled grand rounds sessions across both study periods and all assessments (baseline, post-session, washout, and 3-month follow-up)
  • Willing to provide written informed consent and comply with all study procedures, including wearing the Empatica E4 wristband during teaching sessions

Exclusion criteria

  • Scheduled off-service rotations, vacation, or other commitments that would prevent attendance at any study session or assessment
  • Uncorrected severe visual or auditory impairment that would limit participation in multimedia-based gamified sessions or case presentations
  • History of skin conditions or allergies that would preclude wearing the Empatica E4 wristband (e.g., contact dermatitis)
  • Inability to provide informed consent (e.g., cognitive impairment or language barrier)

Treatment and study plan

Gamified Neurology Grand Rounds

Behavioral

A web-based interactive teaching platform using team-based clinical simulation, real-time decision feedback, points, leaderboards, and blockchain-minted NFT achievement badges. Four 55-minute sessions delivered over 2 weeks. Cases cover stroke, epilepsy, movement disorders, neuroinfectious diseases, neurodegenerative disorders, neuro-ophthalmology, headache, and spinal cord disorders. Participants work in teams of 3-4, make sequential diagnostic/treatment decisions, and receive immediate feedback. Instructor delivers 15-minute expert debrief after 40 minutes of simulation.

Traditional Component

Behavioral

Instructor-led PowerPoint lecture covering identical case content as gamified sessions. Linear presentation: history → physical exam → localization → etiology → differential diagnosis → management. Intermittent Q&A encouraged. No game elements, simulation, points, leaderboards, or blockchain incentives. Four 55-minute sessions delivered over 2 weeks.

Primary outcomes

  1. Immediate Knowledge Acquisition (Post-Session Test Score)

    Time frame: Within 30 minutes after each grand rounds session (8 total sessions per participant; measured across both study periods, Weeks 1-2 and Weeks 7-8)

    Standardized 15-item multiple-choice quiz assessing comprehension of case localization, etiology, differential diagnosis, and management. Each item has one correct answer. Score is percentage correct (0-100%). Tests are administered immediately following each grand rounds session. Internal consistency confirmed via pilot testing (Cronbach's α ≥ 0.7).

  2. 3-Month Knowledge Retention (Delayed Retention Test Score and Retention Rate)

    Time frame: 3 months (± 2 weeks) after completion of Period 2 intervention (Week 8)

    Parallel-form 15-item multiple-choice test matching the immediate post-test in blueprint, difficulty, and internal consistency, but with different question wording and distractor options. Retention rate is calculated as (3-month test score / average immediate post-test score across both periods) × 100%. Higher scores indicate better long-term retention.

Secondary outcomes

  1. Diagnostic Redundancy Ratio

    Time frame: During each grand rounds session (8 total sessions; Weeks 1-2 and Weeks 7-8)

    Efficiency of clinical reasoning measured as the ratio of actual diagnostic tests ordered by a participant/team to the minimal necessary tests defined by expert consensus. Lower ratio indicates more efficient test selection. For gamified sessions, data extracted from platform clickstream logs; for traditional sessions, recorded by research assistant during Q&A.

  2. Time to Key Information Extraction

    Time frame: During each grand rounds session (8 total sessions; Weeks 1-2 and Weeks 7-8)

    Speed of accurate clinical localization. For gamified sessions: number of click steps from case start to first correct localization decision. For traditional sessions: minutes from session start to first correct verbal localization response. Shorter time indicates more efficient reasoning.

  3. Learner Engagement - Interaction Frequency

    Time frame: During each grand rounds session (8 total sessions; Weeks 1-2 and Weeks 7-8)

    Frequency of voluntary learning behaviors. For traditional sessions: number of hand-raises, questions asked, or comments made (recorded by research assistant). For gamified sessions: clickstream depth (average interactions per minute, including decisions, feedback reviews, leaderboard checks). Higher values indicate greater engagement.

  4. Flow Experience

    Time frame: Within 10 minutes after each grand rounds session (8 total sessions; Weeks 1-2 and Weeks 7-8)

    Self-reported immersion and absorption during the learning session. Measured using a single-item slider question: "During this session, I felt completely immersed and lost track of time." Response range: 0 (not at all) to 100 (completely). Administered immediately after each session.

  5. Subjective Cognitive Load

    Time frame: Within 10 minutes after each grand rounds session (8 total sessions; Weeks 1-2 and Weeks 7-8)

    Perceived mental effort required to follow the session. Measured using the Paas 9-point Likert scale (1 = very low cognitive load, 9 = very high cognitive load). Administered immediately after each session.

  6. Instructor Pacing Adjustment Effectiveness

    Time frame: During gamified grand rounds sessions only (4 sessions per participant in crossover arms; Weeks 1-2 for Sequence A, Weeks 7-8 for Sequence B)

    Impact of real-time cognitive load alerts on group cognitive load. Measured as the change in Group Cognitive Load Index (GCLI) slope from 5 minutes before to 5 minutes after an instructor receives an adaptive alert (GCLI >80% or <30% for ≥2 minutes). Negative slope change indicates successful load reduction.

  7. Perceived Value of Blockchain Badges

    Time frame: At 3-month follow-up (Week 20, ±2 weeks)

    Usefulness and ease of use of the NFT achievement badge system. Measured using a modified Technology Acceptance Model (TAM) survey with 7-point Likert scales (1 = strongly disagree, 7 = strongly agree). Subscales: perceived usefulness (e.g., "Badges help me track learning progress") and perceived ease of use (e.g., "Digital wallet is easy to use").

  8. Self-Directed Learning Behavior

    Time frame: During the 3-month period following completion of Period 2 (Weeks 8-20)

    Voluntary educational activities following study completion. Measured via: (1) frequency of neurology textbook/journal borrowing from institutional library, and (2) completion rate of optional online neurology courses recorded in the residency learning management system. Higher values indicate greater sustained motivation.

Sponsors and collaborators

Lead sponsor

West China Hospital

Other

Registry information

Official study title

Gamification vs. Traditional Teaching in Neurology Grand Rounds: A Randomized Crossover Trial Integrating Cognitive Load Monitoring and Blockchain Incentives

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 19, 2026
Registry last updated
Feb 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.