Gastro-enterolgy surgical center, Mansoura University
Al Mansurah, Al-Dakahleia, 35516, Egypt
NCT Number: NCT03693820
Early postoperative pain is a common complaint after elective laparoscopic cholecystectomy. Persistent acute postoperative pain is the dominating complaint and the primary reason for a prolonged stay after this procedure. This pain can be superficial incisional wound pain (somatic), deep visceral pain and/or post-laparoscopy shoulder pain (referred somatic), all of which may require systemic analgesia. Hypothesis: Laparoscopic pain can be superficial incisional wound pain (somatic pain), deep visceral pain and/or post-laparoscopy shoulder pain (referred somatic pain), so the block must be periportal for incisional wound pain, intraperitoneal to decrease pain caused by pneumoperitoneum, and of the bladder bed to decrease the deep visceral pain. This combination can give the maximum analgesia after laparoscopic cholecystectomy.
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Notify Me20 year–60 year
All sexes
Interventional
Not applicable
Al Mansurah, Al-Dakahleia, 35516, Egypt
Bladder bed irrigation with Bupivacaine was an effective method for reducing pain during the first postoperative hours after laparoscopic cholecystectomy. The intraperitoneal administration of lidocaine solution (total dose, 3.5 mg/kg) will be done as follows: immediately after creation of the pneumoperitoneum, the surgeon will spray 50-75 ml of the total solution on the upper surface of the liver under the right sub-diaphragmatic space, and another 50-75ml of the total solution under the left sub-diaphragmatic space. In order to allow the sprayed solution to diffuse under the diaphragmatic space, the Trendelenburg position will be maintained for 2 minutes.
In the infiltration group will be administrating 5 ml lidocaine at each port site before incision, then the surgeon will spray 50-75 ml of the total solution on the upper surface of the liver under the right sub-diaphragmatic space, and another 50-75ml of the total solution under the left sub-diaphragmatic space then 50 ml will be infiltrated in the bladder bed after clamping of the cystic duct and cystic artery. CO2 will be humidified and wormed.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
the 50 ml prepared for gallbladder bed infiltration will be replaced by saline.
Time frame: postoperative, for 24 hours
ketorolac and morphine in mg .
Time frame: postoperative, for 24 hours
hours
Time frame: intraoperative
microgram
Time frame: postoperative at 0, 2, 4, 8, 12, 16 and 24 hours
visual analog score from 0-10, zero is no pain, 10 is the most imaginable pain,
Time frame: basal and intraoperatively every 30 minutes, then at 0, 2, 4, 8, 12, 16 and 24 hours post-operatively.
beat/ minute
Time frame: basal and intraoperatively every 30 minutes, then at 0, 2, 4, 8, 12, 16 and 24 hours post-operatively.
mmHg
Time frame: postoperatively, during the first 24 hours
number
Time frame: postoperatively, after the first night.
through a score 0-2, where 0= good quite sleep, 1= fair sleep, 2= bad quality of sleep.
Time frame: postoperative after 24 hour.
using visual analog score from 0-10. zero = no satisfaction, 12= maximum satisfaction.
Time frame: postoperative within 1 hour.
using visual analog score from 0-10. zero = no satisfaction, 10= maximum satisfaction.
Alaa Mazy Mazy
Other
The Effect of Gallbladder Bed Infiltration on Analgesia in Laparoscopic Cholecystectomy
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