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NCT Number: NCT04062292

Gait Parameters and Balance in Patients With Obstructive Lung Diseases

In the literature, most of the studies examining the gait characteristics and balance separately or examining the relationship between them are on patients with COPD.

No study examining gait parameters in other obstructive pulmonary patients such as bronchiectasis and asthma was found.A convincing link between gait disturbances and falls in COPD patients is still unknown and further research is needed. Therefore, the purpose of our study; gait parameters and balance in individuals with obstructive pulmonary disease. We will also examine the relationship between gait parameters and extrapulmonary clinical indicators of these individuals.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Naciye Vardar-Yagli

Ankara, 06100, Turkey (Türkiye)

Location status: Recruiting

Location contact

Deniz Inal-Ince, PhD

SUB_INVESTIGATOR

Ebru Calik-Kutukcu, PhD

SUB_INVESTIGATOR

Melda Saglam, PhD

SUB_INVESTIGATOR

Naciye Vardar-Yagli, PhD

CONTACT

[email protected]

+903123051576 ext. 123

About this study

Patients with COPD call walking as one of the most problematic activities in daily life. Patients with COPD walk less in daily life than their healthy peers. Gait characteristics of extrapulmonary comorbidities that probably affect the musculoskeletal and cardiovascular system vary. The gait assessment gives an idea about the biomechanical factors associated with a reduction in walking distance in COPD patients. In patients with COPD, after the onset of shortness of breath or leg fatigue, a decrease in cadence during walking, shortened stride length, an increase in the time spent in the double support period, an increase in the peak ankle dorsi flexion moment is observed. During gait, there is an increase in balance disorders in the mediolateral direction. In addition, patients with COPD walk on a constant speed treadmill with more stride time and less step width variability. Studies have shown that patients with COPD have increased temporal walking characteristics, decreased step and stride length, and increased walking variability.

In the literature, most of the studies that examine gait characteristics and balance separately or examine the relationship between them are on patients with COPD. No study examining gait parameters in other obstructive pulmonary patients such as bronchiectasis and asthma has been found. A persuasive link between walking disorders and falls in COPD patients is still unknown and further research is needed. This study will contribute to clarifying the mechanisms of why the balance studied in patients with COPD is adversely affected.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for Obstructive Lung Diseases

  • Being diagnosed with obstructive lung disease,
  • Have not experienced acute exacerbation or infection in the last 1 week,
  • To be between 18-65 years,
  • Volunteering for research,
  • To be able to walk and cooperate.

Exclusion criteria

for Obstructive Lung Diseases:

  • Use walking aid or be chronic oxygen support
  • To have orthopedic or neuromuscular comorbidities that may affect walking patterns.
  • Having had lung cancer, sarcoidosis, tuberculosis disease or lung surgery.

Inclusion criteria

for Healthy People 1.18-65 years of age, 2. Volunteer to participate in the research, 3. To be able to walk and cooperate.

Exclusion criteria

for Healthy People

  • Having any cardiopulmonary disease,
  • To have an advanced orthopedic disease that may affect functional capacity measurement and gait patterns.

Treatment and study plan

Primary outcomes

  1. Gait parameters

    Time frame: 01.09.2020-08.07.2021

    Gait parameters will be assessed with Biodex Gait Trainer (Biodex Medical Systems, Shirley, New York) for six minutes.

Secondary outcomes

  1. Functional Balance and Fall Risk

    Time frame: 01.09.2020-08.07.2021

    Timed Up and Go Test

  2. Functional Exercise Capacity

    Time frame: 01.09.2020-08.07.2021

    6 minute walking test with Moxy device on M.Vastus Lateralis

  3. Respiratory Muscle Strength

    Time frame: 01.09.2020-08.07.2021

    Respiratory muscle strength parameters (maximal inspiratory and maximal expiratory pressure) measurement using mouth pressure device

  4. Peripheral Muscle Strength

    Time frame: 01.09.2020-08.07.2021

    Muscle strength of the knee extensors, hip extensors, shoulder abductors, trunk flexors and trunk extensors will be evaluated by hand dynamometer (Lafayette Manual Muscle Tester Model 01165-USA). Jamar Hand Dynamometer (USA) will measure the hand grip force

  5. Cognitive Status

    Time frame: 01.09.2020-08.07.2021

    Mini Mental Test

Study contacts

Contact information is provided by the study sponsor or research team.

Naciye Vardar-Yagli, PhD

CONTACT

[email protected]

+903123051576 ext. 123

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

Investigation of Gait Parameters and Balance in Patients With Obstructive Lung Diseases

Important dates

Study start
2019
Primary completion
2024
Study completion
2024
First posted
Aug 20, 2019
Registry last updated
Aug 30, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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