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Completed

NCT Number: NCT04842188

Furcation Treatment With L-PRF and aPDT

To treat grade II periodontally diseased furcation areas Leukocyte-Platelet Rich Fibrin (L-PRF) combined with antimicrobial Photo-Dynamic Therapy (a-PDT) was used.

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Key information

Conditions

Furcation Defects Mouth Diseases Periodontal Diseases Stomatognathic Diseases

Age range

32 year–48 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

faculty of dentistry, kafrelsheikh University

Kafr ash Shaykh, 214312, Egypt

About this study

randomized, triple-blinded study (patient, clinician and biostatistician). Twenty-four patients with Grade II furcation involvement were recruited in this study.

Control group only received L-PRF, while study group used a combination of L-PRF and aPDT Attachment level, pocket depth, horizontal component and gingival recession, also radiographic Bone depth, width, height and volume were were recorded at baseline and postoperatively after 6 months

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Grade II furcation involvement
  • age range 18- 50 years
  • 3 mm or more vertical probing depth

Exclusion criteria

  • systemic disease
  • abnormal clotting and bleeding
  • smokers,
  • root caries or restoration
  • Grade II mobility
  • periapical lesions

Treatment and study plan

L-PRF with aPDT

Procedure

surgical open flap debridement followed by L-PRF with aPDT

L-PRF

Procedure

surgical open flap debridement followed by L-PRF alone

Primary outcomes

  1. Clinical evaluation of Vertical clinical attachment level VCAL

    Time frame: 6 months

    using periodontal probe in mm

  2. clinical evaluation of vertical pocket depth VPD

    Time frame: 6 months

    using periodontal probe in mm

  3. clinical evaluation of furcation horizontal component FHC

    Time frame: 6 months

    using periodontal probe in mm

  4. clinical evaluation of gingival recession REC

    Time frame: 6 months

    using periodontal probe in mm

Sponsors and collaborators

Lead sponsor

Kafrelsheikh University

Other

Registry information

Official study title

Evaluation of Leukocyte Platelet Rich Fibrin With Antimicrobial Photodynamic Therapy in Treatment of Furcation Involvement: Randomised Clinical Study

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Apr 13, 2021
Registry last updated
Jun 24, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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