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OpenTrials
Completed

NCT Number: NCT03693352

Functional Residual Capacity Measured by Capnography in Ventilated Patients

Changes in body position during anesthesia can alter functional residual capacity and gas exchange. The monitoring of such changes in functional residual capacity is difficult at the bedside. The present study was designed to determine if volumetric capnography can detect changes in the functional residual capacity during surgery.

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Key information

Conditions

Respiratory Physiological Phenomena

Age range

30 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hospital Privado de Comunidad

Mar del Plata, Buenos Aires, 7600, Argentina

About this study

This is a prospective and observational study designed to test the reliability of the capnodynamic equation to determine changes in functional residual capacity measured during anesthesia. The investigators will studied 40 mechanically ventilated patients undergoing general anesthesia. Functional residual capacity will be continuously measured in a non invasive way using expired carbon dioxide. Changes in functional residual capacity with standard modification in body positioning (Trendelenburg or anti-Trendelenburg position) and ventilatory settings wiil be tested.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Written Inform Consent
  • Programmed surgery
  • Laparoscopic surgery
  • Supine position

Exclusion criteria

  • Emergency surgery
  • Chronic respiratory disease
  • Active smoking

Treatment and study plan

Primary outcomes

  1. Functional Residual Capacity Measured by Capnography in Ventilated Patients

    Time frame: 6 hours

    Measurement of functional residual capacity with capnography with body positioning changes.

Sponsors and collaborators

Lead sponsor

Hospital Privado de Comunidad de Mar del Plata

Other

Registry information

Official study title

Effect of Positive End-expiratory Pressure on Functional Residual Capacity Measured by Volumetric Capnography in Mechanically Ventilated Patients

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Oct 3, 2018
Registry last updated
Jul 14, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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